AP0773

antibody from Bioworld Technology, Inc
Targeting: ATG2B C14orf103, FLJ10242
Provider product page for AP0773
Western blot
Immunohistochemistry

Antibody data

Product number
AP0773 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ATG2B polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ATG2B.
Description
Atg2B (ATG2 autophagy related 2 homolog B) is a 2,078 amino acid protein belonging to the ATG2 family. Encoded by a gene that maps to human chromosome 14q32.2, Atg2B is conserved in chimpanzee, canine, bovine, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. 16 known human ATG genes exist, of which four (Atg2B, Atg5, Atg9B and Atg12) possess mononucleotide repeats with seven or more nucleotides. Atg2B frameshift mutations may contribute to development of cancer via disruption of autophagy. Atg2B associates with Atg2A, which is also linked to frameshift mutations associated with gastric and colorectal carcinomas with high microsatellite instability, indicating that these two related proteins functionally interact. WIPI-4, which is phylogenetically related to both Atg18p and Atg21p, associates with Atg2B and reciprocally binds Atg2A.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ATG2B protein structure - AP0773 shown in red.