Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1449993 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Autophagy Related 2B (ATG2B) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.
Autophagy as a cell death and tumor suppressor mechanism.
Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Velikkakath AK, Nishimura T, Oita E, Ishihara N, Mizushima N
Molecular biology of the cell 2012 Mar;23(5):896-909
Molecular biology of the cell 2012 Mar;23(5):896-909
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, Ahn CH, Yoo NJ, Lee SH
The Journal of pathology 2009 Apr;217(5):702-6
The Journal of pathology 2009 Apr;217(5):702-6
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y
The Journal of cell biology 2000 Sep 18;150(6):1507-13
The Journal of cell biology 2000 Sep 18;150(6):1507-13
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5
Carcinogenesis 1993 Dec;14(12):2501-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ATG2B in K562 cell lysate with ATG2B antibody Cat.-No AP55489PU-N at (A) 1 and (B) 2 ?g/ml.