BS61270

antibody from Bioworld Technology, Inc
Targeting: SH2D4A FLJ20967, PPP1R38, SH2A
Provider product page for BS61270

Antibody data

Product number
BS61270 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SH2D4A polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human SH2D4A.
Description
SH2D4A (SH2 domain containing protein 4A), also known as SH2A, is a ubiquitously expressed 454 amino acid docking protein that belongs to the SH2 signaling protein family. Members of this family typically participate in intracellular signaling. Localizing to the cytoplasm, SH2D4A contains one Src homology 2 (SH2) domain. SH2 domains bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. This suggests that SH2D4A, via its SH2 domain, may play an important function in cellular signal transduction. More specifically, SH2D4A is believed to function as an inhibiting factor in PKC signal transduction. In addition, SH2D4A exhibits abnormal expression in various cancers, implying that it may be involved in tumorigenesis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SH2D4A protein structure - BS61270 shown in red.