307005

antibody from BioLegend
Targeting: TNFRSF10C CD263, DcR1, LIT, TRAILR3, TRID
Provider product page for 307005

Antibody data

Product number
307005 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#307005, RRID:AB_2287506
Product name
PE anti-human CD263 (DcR1, TRAIL-R3)
Antibody type
Monoclonal
Antigen
Extracellular domain of DcR1-human IgG1 Fc fusion protein
Description
DcR1 is a 65 kD GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
TNFRSF10C protein structure - 307005 shown in red.