BS3865

antibody from Bioworld Technology, Inc

Targeting: IFI16 IFNGIP1, PYHIN2

Western blot (Data presented on provider website)

Antibody Data

Product number

BS3865

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS3865, RRID:AB_1914259

Product name

IFI 16 (N772) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 740-795 of Human IFI-16.

Description

Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.