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Cell line expression
Protein structure
MVP
Major vault proteinLRP, VAULT1
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Top validated antibodies |
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| GeneTex |  GTX23180 |
1 references | Monoclonal |
WB
ICC
IP
IHC
FC
GS
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| Proteintech Group | 16478-1-AP |
9 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | H00009961-M01 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | MA5-13871 |
4 references | Monoclonal |
WB
IP
IHC
FC
GS
OA
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| Abnova Corporation | H00009961-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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