Tissue expression
Cell line expression
Protein structure
BIRC3
Baculoviral IAP repeat containing 3API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
Top validated antibodies |
|||||
| Proteintech Group | 17 references | Polyclonal |
|
||
| antibodies-online | 2 references | Polyclonal |
|
||
| Novus Biologicals | 2 references | Polyclonal |
|
||
| Invitrogen Antibodies | 1 references | Polyclonal |
|
||
| LSBio | Polyclonal |
|
|||