Tissue expression
Cell line expression
Protein structure
SDHA
Succinate dehydrogenase complex flavoprotein subunit AFP, SDH2, SDHF
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
83 references | Monoclonal |
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Proteintech Group | ![]() |
97 references | Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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