Tissue expression
Cell line expression
Protein structure
FAP
Fibroblast activation protein alphaDPPIV
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Top validated antibodies |
|||||
Invitrogen Antibodies | PA5-99458 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
antibodies-online | ABIN394545 | 5 references | Monoclonal |
WB
EL
IP
|
|
Novus Biologicals | H00002191-M01 | 6 references | Monoclonal |
WB
EL
IP
|
|
Abnova Corporation | H00002191-M01 | 4 references | Monoclonal |
WB
EL
IP
|
|
R&D Systems | AF3715 | 8 references | Polyclonal |
WB
IP
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider