BTAF1

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]

Description

B-TFIID TATA-box binding protein associated factor 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

10 (91923770 - 92030325)

Ensembl ID

ENSG00000095564  (ver. 103.38)

Orthologs

Mouse Btaf1: ENSMUSG00000040565

UniProt

O14981

neXtProt

NX_O14981

Human splice variants
Mouse splice variants

Protein structure