Tissue expression
Cell line expression
Protein structure
HNF4A
Hepatocyte nuclear factor 4 alphaHNF4, MODY, MODY1, NR2A1, TCF14
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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| Invitrogen Antibodies | 7 references | Monoclonal |
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| Novus Biologicals | 6 references | Monoclonal |
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| R&D Systems | 6 references | Monoclonal |
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| Atlas Antibodies | 10 references | Polyclonal |
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| antibodies-online | 5 references | Monoclonal |
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