Tissue expression
Cell line expression
Protein structure
BMP7
Bone morphogenetic protein 7OP-1
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
Top validated antibodies |
|||||
| Proteintech Group | 20 references | Polyclonal |
|
||
| Novus Biologicals | 1 references | Monoclonal |
|
||
| Invitrogen Antibodies | Polyclonal |
|
|||
| LSBio | Polyclonal |
|
|||
| antibodies-online | 4 references | Polyclonal |
|
||