Tissue expression
Cell line expression
Protein structure
MIB1
Mindbomb E3 ubiquitin protein ligase 1DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
Top validated antibodies |
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Proteintech Group | ![]() |
7 references | Polyclonal |
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Abnova Corporation | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
Monoclonal |
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LSBio | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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