Tissue expression
Cell line expression
Protein structure
RGCC
Regulator of cell cyclebA157L14.2, C13orf15, RGC-32, RGC32
This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | 44450002 | 4 references | Polyclonal |
WB
EL |
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Biorbyt | orb525955 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN4350298 | Polyclonal |
WB
ICC
IHC
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Invitrogen Antibodies | MA5-24460 | Monoclonal |
EL
ICC
OA
|
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Bioss | bs-9079R | 1 references | Polyclonal |
ICC
IHC |
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