Tissue expression
Cell line expression
Protein structure
TYK2
Tyrosine kinase 2JTK1
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Sep 2020]
Top validated antibodies |
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| Abnova Corporation | Monoclonal |
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| Novus Biologicals | Monoclonal |
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| LSBio | Polyclonal |
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| Proteintech Group | 1 references | Polyclonal |
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| Invitrogen Antibodies | 2 references | Polyclonal |
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