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SERPINE1
Serpin family E member 1PAI, PAI1, PLANH1
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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| Proteintech Group |  13801-1-AP |
22 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-17171 |
5 references | Monoclonal |
WB
IHC
FC
OA
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| antibodies-online | ABIN969566 |
2 references | Monoclonal |
WB
EL
IHC
FC
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| Novus Biologicals | NBP1-19773 |
15 references | Polyclonal |
WB
EL
ICC
IHC
|
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| R&D Systems | AF1786 |
2 references | Polyclonal |
WB
IP
IHC
BN
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