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Cell line expression
Protein structure
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3LH3
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11027-1-AP |
33 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 11027-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| NovoPro Bioscience Inc. | 107477 |
Monoclonal |
WB
EL
ICC
IP
IHC
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| FineTest Biotech | FNab06553 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| Biorbyt | orb395457 |
Monoclonal |
WB
EL
ICC
IP
IHC
|
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