Tissue expression
Cell line expression
Protein structure
MICU1
Mitochondrial calcium uptake 1CALC, CBARA1, EFHA3, FLJ12684
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Top validated antibodies |
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| Atlas Antibodies | 6 references | Polyclonal |
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| Novus Biologicals | 6 references | Polyclonal |
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| LSBio | Monoclonal |
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| NSJ Bioreagents | Polyclonal |
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| Everest Biotech | Polyclonal |
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