FOLR3

This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Description

Folate receptor gamma

Tissue specificity

Group enriched (bone marrow, lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

11 (72114869 - 72139892)

Ensembl ID

ENSG00000110203  (ver. 103.38)

Orthologs

-

UniProt

P41439

neXtProt

NX_P41439

Human splice variants

Protein structure