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Cell line expression
Protein structure
LIFR
LIF receptor subunit alphaCD118
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
Top validated antibodies |
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| Proteintech Group |  22779-1-AP |
16 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 22779-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| GeneTex | GTX60183 |
1 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| NovoPro Bioscience Inc. | 112221 |
Polyclonal |
WB
EL
IP
IHC
FC
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| LSBio | LS-C670584 |
Polyclonal |
WB
EL
ICC
IHC
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