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Protein structure
ABCD3
ATP binding cassette subfamily D member 3PMP70, PXMP1, ZWS2
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA1-650 |
29 references | Polyclonal |
WB
ICC
FC
OA
|
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| GeneTex | GTX80693 |
1 references | Monoclonal |
WB
ICC
IP
ChIP
OA
|
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| Atlas Antibodies | HPA032027 |
1 references | Polyclonal |
ICC
IHC
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| Novus Biologicals | NBP1-20871 |
3 references | Polyclonal |
WB
EL
IHC
|
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| OriGene | TA310768 |
1 references | Monoclonal |
WB
FC
OA
|
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