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Protein structure
PI3
Peptidase inhibitor 3cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]
Top validated antibodies |
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| R&D Systems |  AF1747 |
3 references | Polyclonal |
WB
EL
IP
BN
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| Invitrogen Antibodies | PA5-79818 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Atlas Antibodies | HPA017737 |
1 references | Polyclonal |
WB
IHC
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| Boster Biological Technology | PB9957 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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| Novus Biologicals | AF1747 |
3 references | Polyclonal |
WB
IP
BN
|
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