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Protein structure
PZP
PZP alpha-2-macroglobulin likeCPAMD6
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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| Proteintech Group |  21742-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-110249 |
1 references | Polyclonal |
WB
OA
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| NovoPro Bioscience Inc. | 114181 |
Polyclonal |
WB
EL
IHC
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| Wuhan Fine Biotech Co., Ltd. | FNab06763 |
Polyclonal |
WB
EL
IHC
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| R&D Systems | MAB8280 |
Monoclonal |
WB
EL
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