Tissue expression
Cell line expression
Protein structure
PCNA
Proliferating cell nuclear antigenThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 32 references | Monoclonal |
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| Proteintech Group | 878 references | Polyclonal |
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| Invitrogen Antibodies | 213 references | Monoclonal |
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| GeneTex | 17 references | Monoclonal |
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| antibodies-online | 5 references | Monoclonal |
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