Tissue expression
Cell line expression
Protein structure
SMPD4
Sphingomyelin phosphodiesterase 4FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3
The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017]
Top validated antibodies |
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Atlas Antibodies | HPA049426 | Polyclonal |
WB
ICC
IHC
|
||
Invitrogen Antibodies | PA5-61966 | Polyclonal |
WB
ICC
IHC
|
||
antibodies-online | ABIN4354849 | Polyclonal |
WB
ICC
IHC
|
||
Novus Biologicals | NBP2-33567 | Polyclonal |
WB
ICC
IHC
|
||
NovoPro Bioscience Inc. | 127872 | Polyclonal |
WB
EL
IHC
|
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