Tissue expression
Cell line expression
Protein structure
STAM
Signal transducing adaptor moleculeSTAM1
This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Top validated antibodies |
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| Proteintech Group | 18 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Abnova Corporation | Monoclonal |
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| LSBio | Polyclonal |
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| antibodies-online | Monoclonal |
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