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Protein structure
PPM1B
Protein phosphatase, Mg2+/Mn2+ dependent 1BPP2CB, PP2CBETA, PPC2BETAX
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00005495-M01 |
1 references | Monoclonal |
WB
EL
ICC
IP
BN
PLA
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| Abnova Corporation | H00005495-M01 |
Monoclonal |
WB
EL
ICC
IP
PLA
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| Proteintech Group | 13193-1-AP |
5 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN393440 |
Monoclonal |
WB
EL
ICC
IP
IHC
|
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| LSBio | LS-C197966 |
Monoclonal |
WB
EL
ICC
IP
|
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