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ECE2
Endothelin converting enzyme 2KIAA0604, MGC2408
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| Proteintech Group |  15418-1-AP |
1 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 15418-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| R&D Systems | AF1645 |
2 references | Polyclonal |
WB
IP
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| Novus Biologicals | AF1645 |
2 references | Polyclonal |
WB
IP
|
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| antibodies-online | ABIN733958 |
1 references | Polyclonal |
WB
ICC
IHC
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