ZNF185

Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2010]

Description

Zinc finger protein 185 with LIM domain

Tissue specificity

Tissue enhanced (epididymis, esophagus)

Subcell location

Plasma membrane, Actin filaments, Focal adhesion sites, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (152914442 - 152973480)

Ensembl ID

ENSG00000147394  (ver. 103.38)

Orthologs

Mouse Zfp185: ENSMUSG00000031351

UniProt

O15231

neXtProt

NX_O15231

Human splice variants
Mouse splice variants

Protein structure