Tissue expression
Cell line expression
Protein structure
UBR1
Ubiquitin protein ligase E3 component n-recognin 1The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00197131-M01 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN566929 | 1 references | Monoclonal |
WB
EL |
|
Abnova Corporation | H00197131-M01 | 1 references | Monoclonal |
WB
EL |
|
Invitrogen Antibodies | 26069-1-AP | Polyclonal |
IP
IHC
OA
|
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Proteintech Group | 26069-1-AP | Polyclonal |
EL
IP
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider