Tissue expression
Cell line expression
Protein structure
CXCR1
C-X-C motif chemokine receptor 1CD181, CDw128a, CKR-1, CMKAR1, IL8RA
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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R&D Systems | ![]() |
32 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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GeneTex | ![]() |
2 references | Polyclonal |
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Proteintech Group | ![]() |
8 references | Polyclonal |
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antibodies-online | ![]() |
Monoclonal |
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