Tissue expression
Cell line expression
Protein structure
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta14-3-3-zeta, KCIP-1, YWHAD
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Abnova Corporation | 4 references | Polyclonal |
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| antibodies-online | 2 references | Polyclonal |
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| GeneTex | 3 references | Polyclonal |
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