Tissue expression
Cell line expression
Protein structure
SPRED1
Sprouty related EVH1 domain containing 1FLJ33903, PPP1R147
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
4 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
4 references | Polyclonal |
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