Tissue expression
Cell line expression
Protein structure
RHOH
Ras homolog family member HARHH, TTF
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]
Top validated antibodies |
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| LSBio | Polyclonal |
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| OriGene | Polyclonal |
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| antibodies-online | Polyclonal |
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| Acris Antibodies GmbH | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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