Tissue expression
Cell line expression
Protein structure
PTGER4
Prostaglandin E receptor 4EP4
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NLS3898 | 2 references | Polyclonal |
WB
ICC
IHC
FC |
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Proteintech Group | 24895-1-AP | 6 references | Polyclonal |
WB
EL
IHC
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LSBio | LS-B6947 | Polyclonal |
WB
ICC
IHC
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antibodies-online | ABIN486221 | 1 references | Polyclonal |
WB
EL
ICC
|
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Atlas Antibodies | HPA012756 | 1 references | Polyclonal |
WB
IHC |
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