GCSAM

This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Description

Germinal center associated signaling and motility

Tissue specificity

Group enriched (lymphoid tissue, skin)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

3 (112120839 - 112133270)

Ensembl ID

ENSG00000174500  (ver. 103.38)

Orthologs

Mouse Gcsam: ENSMUSG00000022659

UniProt

Q8N6F7

neXtProt

NX_Q8N6F7

Human splice variants
Mouse splice variants

Protein structure