Tissue expression
Cell line expression
Protein structure
FZD4
Frizzled class receptor 4CD344, EVR1
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| R&D Systems | 2 references | Monoclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| Boster Biological Technology | 2 references | Polyclonal |
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