Tissue expression
Cell line expression
Protein structure
CDH4
Cadherin 4This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Top validated antibodies |
|||||
Abnova Corporation | PAB1864 | 3 references | Polyclonal |
WB
ICC
IHC
FC |
|
Invitrogen Antibodies | PA5-16766 | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
||
antibodies-online | ABIN2158175 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
Abgent | AP1401A | Polyclonal |
WB
ICC
IHC
FC |
||
NSJ Bioreagents | F54374 | Polyclonal |
WB
ICC
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider