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Protein structure
PUF60
Poly(U) binding splicing factor 60FIR, RoBPI, SIAHBP1
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Top validated antibodies |
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| LSBio |  LS-B10758 |
Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 10810-1-AP |
2 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN2493200 |
Polyclonal |
WB
ICC
IHC
FC
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| Novus Biologicals | NB100-1125 |
2 references | Polyclonal |
WB
EL
IHC
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| FineTest Biotech | FNab06954 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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