Tissue expression
Cell line expression
Protein structure
NEU1
Neuraminidase 1NEU
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
4 references | Monoclonal |
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LSBio | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
4 references | Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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OriGene | ![]() |
1 references | Monoclonal |
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