Tissue expression
Cell line expression
Protein structure
VAMP2
Vesicle associated membrane protein 2SYB2, VAMP-2
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NB300-595 | 5 references | Polyclonal |
WB
ICC
IP
IHC
FC
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Proteintech Group | 10135-1-AP | 25 references | Polyclonal |
WB
EL
IHC
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Invitrogen Antibodies | OSS00035W | 2 references | Polyclonal |
WB
ICC
IHC
OA |
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antibodies-online | ABIN407569 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
OriGene | AM05628PU-S | 1 references | Monoclonal |
WB
EL
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider