F2RL2

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]

Description

coagulation factor II (thrombin) receptor-like 2

Protein family

GPCRs excl olfactory receptors, Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP

Chromosome

5:q13.3 (75911328 - 75919259)

Ensembl ID

ENSG00000164220  (ver. 69.37)

Orthologs

Mouse F2rl2: ENSMUSG00000021675

Human splice variants
Mouse splice variants