ADRBK1
gene productBARK1, GRK2
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
Featured antibodies
Thermo Fisher Scientific Pierce |
MA5-15840 | 0 references | Monoclonal |
WB ![]() EL ![]() IF ![]() IH ![]() |
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