ITK

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

Description

IL2-inducible T-cell kinase

Protein family

Enzymes, Kinases, Mapped to UniProt SWISS-PROT, Mutated genes in cancer, SH2-domain containing proteins, SH3-domain containing proteins

Chromosome

5:q33.3 (156569944 - 156682201)

Ensembl ID

ENSG00000113263  (ver. 71.37)

Orthologs

Mouse Itk: ENSMUSG00000020395

Human splice variants
Mouse splice variants