FZD4

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

Description

frizzled family receptor 4

Protein family

CD markers, GPCRs excl olfactory receptors, Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP

Chromosome

11:q14.2 (86656721 - 86666433)

Ensembl ID

ENSG00000174804  (ver. 69.37)

Orthologs

Mouse Fzd4: ENSMUSG00000049791

Human splice variants
Mouse splice variants