ADORA1

The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]

Description

adenosine A1 receptor

Protein family

GPCRs excl olfactory receptors, Membrane proteins predicted by MDM, Transporters

Chromosome

1:q32.1 (203059782 - 203136533)

Ensembl ID

ENSG00000163485  (ver. 69.37)

Orthologs

Mouse Adora1: ENSMUSG00000042429

Human splice variants
Mouse splice variants