SDHA

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. [provided by RefSeq, Jul 2008]

Description

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Protein family

Enzymes

Chromosome

5:p15.33 (218356 - 256815)

Ensembl ID

ENSG00000073578  (ver. 69.37)

Orthologs

Mouse Sdha: ENSMUSG00000021577

Human splice variants
Mouse splice variants