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- Antibody Data
- Antigen structure
- References [261]
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- Western blot [2]
- Immunocytochemistry [9]
- Immunohistochemistry [1]
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- Product number
- PA3-900 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Calreticulin Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- PA3-900 detects calreticulin from human, non-human primate, rabbit, mouse, canine and rat samples.
- Concentration
- Conc. Not Determined
Submitted references Schweinfurthin induces ICD without ER stress and caspase activation.
Endoplasmic reticulum stress-induced release and binding of calreticulin from human ovarian cancer cells.
Geranylgeranyl diphosphate synthase inhibitor and proteasome inhibitor combination therapy in multiple myeloma.
CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation.
Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells.
Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers.
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Local translation in nuclear condensate amyloid bodies.
A Novel Thienopyrimidine Analog, TPH104, Mediates Immunogenic Cell Death in Triple-Negative Breast Cancer Cells.
Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.
Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models.
Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors.
Immunomodulatory activity of IR700-labelled affibody targeting HER2.
Past and ongoing adaptation of human cytomegalovirus to its host.
Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells.
Endothelial calreticulin deletion impairs endothelial function in aged mice.
Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain.
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.
Calreticulin enhances the secretory trafficking of a misfolded α-1-antitrypsin.
Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.
Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death.
Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death.
ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases.
Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity.
The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide.
Dissociation of membrane-chromatin contacts is required for proper chromosome segregation in mitosis.
Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity.
Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models.
Functional differences of short and long isoforms of spastin harboring missense mutation.
Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen.
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer.
SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition.
Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I.
Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans-Presentation.
Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR.
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.
Nesprin-2 Interacts with Condensin Component SMC2.
Association of calreticulin expression with disease activity and organ damage in systemic lupus erythematosus patients.
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways.
A novel approach to assess the ubiquitin-fold modifier 1-system in cells.
FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.
Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants.
Characterization of the ER-Targeted Low Affinity Ca(2+) Probe D4ER.
VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation.
α-Integrin expression and function modulates presentation of cell surface calreticulin.
Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.
Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology.
A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice.
A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.
Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected Primary Fibroblasts.
Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression.
Regulation of calreticulin-major histocompatibility complex (MHC) class I interactions by ATP.
A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.
Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice.
Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses.
Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.
Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.
Calreticulin promotes angiogenesis via activating nitric oxide signalling pathway in rheumatoid arthritis.
Intracellular trafficking of the human cytomegalovirus-encoded 7-trans-membrane protein homologs pUS27 and pUL78 during viral infection: a comparative analysis.
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays.
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells.
The membrane-proximal KXGFFKR motif of α-integrin mediates chemoresistance.
Serum levels of calreticulin in correlation with disease activity in patients with rheumatoid arthritis.
Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.
FRET-based sensor analysis reveals caveolae are spatially distinct Ca2+ stores in endothelial cells.
Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane.
Gas1 interferes with AβPP trafficking by facilitating the accumulation of immature AβPP in endoplasmic reticulum-associated raft subdomains.
Cell-Type-Specific Effects of Silibinin on Vitamin D-Induced Differentiation of Acute Myeloid Leukemia Cells Are Associated with Differential Modulation of RXRα Levels.
Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.
Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Some fine-structural findings on the thyroid gland in Apc1638T/1638T mice that express a C-terminus lacking truncated Apc.
A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles.
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle.
Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms.
Reduced calreticulin levels link endoplasmic reticulum stress and Fas-triggered cell death in motoneurons vulnerable to ALS.
Measurement of activation of the endoplasmic reticulum stress response in autoimmune myositis.
Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism.
Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection.
Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis.
Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus.
Calreticulin-2 is localized in the lumen of the endoplasmic reticulum but is not a Ca2+ -binding protein.
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.
Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase.
Loss of membrane targeting of Vangl proteins causes neural tube defects.
Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells.
'IntraCell' plugin for assessment of intracellular localization of nano-delivery systems and their targeting to the individual organelles.
The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells.
The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function.
Calreticulin binds to gentamicin and reduces drug-induced ototoxicity.
Role of Rab1b in COPII dynamics and function.
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.
Ero1alpha requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM).
A mechanism of release of calreticulin from cells during apoptosis.
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
The sodium/proton exchanger NHE8 regulates late endosomal morphology and function.
Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease.
Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils.
Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).
Dysferlin overexpression in skeletal muscle produces a progressive myopathy.
Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.
Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture.
Association of HTLV Tax proteins with TAK1-binding protein 2 and RelA in calreticulin-containing cytoplasmic structures participates in Tax-mediated NF-κB activation.
Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse.
An arginine stretch limits ADAM10 exit from the endoplasmic reticulum.
Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation.
Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system.
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells.
Differential cell death regulation between adult-unloaded and aged rat soleus muscle.
Transcriptome and proteome analysis of osteocytes treated with nitrogen-containing bisphosphonates.
Chronic stress elicits prolonged activation of alpha-MSH secretion and subsequent degeneration of melanotroph.
A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles.
The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival.
Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules.
Functional characterization of two secreted SEL1L isoforms capable of exporting unassembled substrate.
Intracellular localization of Brucella abortus and Francisella tularensis in primary murine macrophages.
Intracellular localization of Brucella abortus and Francisella tularensis in primary murine macrophages.
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X.
The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading.
A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein.
Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.
Impact of two novel mutations on the structure and function of human myeloperoxidase.
Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library.
The rheumatoid arthritis shared epitope triggers innate immune signaling via cell surface calreticulin.
Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration.
Post-translational arginylation of calreticulin: a new isospecies of calreticulin component of stress granules.
Influence of Ki-ras-driven oncogenic transformation on the protein network of murine fibroblasts.
Isolation of endoplasmic reticulum, mitochondria, and mitochondria-associated membrane fractions from transfected cells and from human cytomegalovirus-infected primary fibroblasts.
Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer.
Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP.
Lycopene and other carotenoids inhibit estrogenic activity of 17beta-estradiol and genistein in cancer cells.
Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.
Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera.
Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites.
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.
Androgen-regulated formation and degradation of gap junctions in androgen-responsive human prostate cancer cells.
Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal.
Effects of aging on Ca2+ signaling in murine mesenteric arterial smooth muscle cells.
Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells.
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.
Mucin granules are in close contact with tubular elements of the endoplasmic reticulum.
Different approaches for assaying melanosome transfer.
C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors.
MAP-1 is a mitochondrial effector of Bax.
Mitochondrially targeted p53 has tumor suppressor activities in vivo.
TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination.
Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia.
Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival.
The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells.
Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells.
Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.
Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.
Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2.
Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.
The cotranslational maturation of the type I membrane glycoprotein tyrosinase: the heat shock protein 70 system hands off to the lectin-based chaperone system.
Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide.
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking.
Newly synthesized hepatitis C virus replicon RNA is protected from nuclease activity by a protease-sensitive factor(s).
HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RII alpha regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling.
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
Activity-dependent expression of inositol 1,4,5-trisphosphate receptor type 1 in hippocampal neurons.
Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation.
Membrane fusion of secretory vesicles of the sea urchin egg in the absence of NSF.
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.
N-glycosylation is crucial for folding, trafficking, and stability of human tripeptidyl-peptidase I.
Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.
Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.
Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.
A new tool for plant cell biology: in vivo antibody uptake in plant protoplasts.
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.
Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle.
Endoplasmic reticulum stress and unfolded protein response in inclusion body myositis muscle.
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation.
An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.
Human T-cell lymphotropic virus type 1 p12I enhances interleukin-2 production during T-cell activation.
A glucose-6-phosphate hydrolase, widely expressed outside the liver, can explain age-dependent resolution of hypoglycemia in glycogen storage disease type Ia.
N-linked oligosaccharide processing, but not association with calnexin/calreticulin is highly correlated with endoplasmic reticulum-associated degradation of antithrombin Glu313-deleted mutant.
Tumor-derived, chaperone-rich cell lysate activates dendritic cells and elicits potent antitumor immunity.
Involvement of the endoplasmic reticulum in peroxisome formation.
Tyrosinase maturation and oligomerization in the endoplasmic reticulum require a melanocyte-specific factor.
N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin.
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane.
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane.
Altered levels and regulation of stathmin in paclitaxel-resistant ovarian cancer cells.
Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilization.
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum.
Localization of p21-activated protein kinase gamma-PAK/Pak2 in the endoplasmic reticulum is required for induction of cytostasis.
Membrane topology of the hepatitis C virus NS2 protein.
Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells.
Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation.
N-linked glycosylation is critical for the plasma membrane localization of nephrin.
Cellular location of proteins related to iron absorption and transport.
Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes.
Identification of glycoprotein gpTRL10 as a structural component of human cytomegalovirus.
Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs.
Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum.
The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
Co-localization of the inositol 1,4,5-trisphosphate receptor and calreticulin in the equatorial segment and in membrane bounded vesicles in the cytoplasmic droplet of human spermatozoa.
nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?
nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?
Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy.
Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy.
Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: insight into the mechanisms of congenital nephrotic syndrome.
ER60/ERp57 forms disulfide-bonded intermediates with MHC class I heavy chain.
Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation.
Calreticulin is an interleukin-3-sensitive calcium-binding protein in human basophil leukocytes.
Endoplasmic reticulum and cis-Golgi localization of human T-lymphotropic virus type 1 p12(I): association with calreticulin and calnexin.
Carnosic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents.
Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin.
Endoplasmic reticulum retention is a common defect associated with tyrosinase-negative albinism.
Rat sperm 2B1 glycoprotein (PH20) contains a C-terminal sequence motif for attachment of a glycosyl phosphatidylinositol anchor. Effects of endoproteolytic cleavage on hyaluronidase activity.
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity.
HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern.
Caveolae from canine airway smooth muscle contain the necessary components for a role in Ca(2+) handling.
Caveolae from canine airway smooth muscle contain the necessary components for a role in Ca(2+) handling.
Different expression of calreticulin and immunoglobulin binding protein in Alzheimer's disease brain.
Specific association of increased cyclin-dependent kinase 5 expression with monocytic lineage of differentiation of human leukemia HL60 cells.
Evidence of [Ca(2+)]i elevation by anti-calreticulin immunoreactive protein in neurons.
Calreticulin couples calcium release and calcium influx in integrin-mediated calcium signaling.
Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at ser128.
Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity.
Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity.
Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules.
ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.
Spreading of the immune response from 52 kDaRo and 60 kDaRo to calreticulin in experimental autoimmunity.
Calnexin association is not sufficient to protect T cell receptor alpha proteins from rapid degradation in CD4+CD8+ thymocytes.
Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins.
Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins.
Calnexin associates with monomeric and oligomeric (disulfide-linked) CD3delta proteins in murine T lymphocytes.
Calnexin associates with monomeric and oligomeric (disulfide-linked) CD3delta proteins in murine T lymphocytes.
Vasostatin, a calreticulin fragment, inhibits angiogenesis and suppresses tumor growth.
MHC class I molecules compete in the endoplasmic reticulum for access to transporter associated with antigen processing.
Differential modulation of SERCA2 isoforms by calreticulin.
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
Calreticulin associates with stress proteins: implications for chaperone function during heat stress.
High density distribution of endoplasmic reticulum proteins and mitochondria at specialized Ca2+ release sites in oligodendrocyte processes.
Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells.
Calreticulin biosynthesis and processing in human myeloid cells: demonstration of signal peptide cleavage and N-glycosylation.
Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand.
Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand.
Interactions between newly synthesized glycoproteins, calnexin and a network of resident chaperones in the endoplasmic reticulum.
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.
The related molecular chaperones calnexin and calreticulin differentially associate with nascent T cell antigen receptor proteins within the endoplasmic reticulum.
Deglucosylation of N-linked glycans is an important step in the dissociation of calreticulin-class I-TAP complexes.
Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes.
Calreticulin expression in spinal motoneurons of the rat.
Intracellular calcium stores and inositol 1,4,5-trisphosphate receptor in rat liver cells.
Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.
Calreticulin inhibits repetitive intracellular Ca2+ waves.
Calreticulin inhibits repetitive intracellular Ca2+ waves.
Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading.
Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading.
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils.
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils.
Zhang R, Neighbors JD, Schell TD, Hohl RJ
Oncoimmunology 2022;11(1):2104551
Oncoimmunology 2022;11(1):2104551
Endoplasmic reticulum stress-induced release and binding of calreticulin from human ovarian cancer cells.
Abdullah TM, Whatmore J, Bremer E, Slibinskas R, Michalak M, Eggleton P
Cancer immunology, immunotherapy : CII 2022 Jul;71(7):1655-1669
Cancer immunology, immunotherapy : CII 2022 Jul;71(7):1655-1669
Geranylgeranyl diphosphate synthase inhibitor and proteasome inhibitor combination therapy in multiple myeloma.
Haney SL, Varney ML, Williams JT, Smith LM, Talmon G, Holstein SA
Experimental hematology & oncology 2022 Feb 9;11(1):5
Experimental hematology & oncology 2022 Feb 9;11(1):5
CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation.
Sampieri L, Funes Chabán M, Di Giusto P, Rozés-Salvador V, Alvarez C
Frontiers in molecular neuroscience 2021;14:650338
Frontiers in molecular neuroscience 2021;14:650338
Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells.
Calì T, Brini M
Nature protocols 2021 Nov;16(11):5287-5308
Nature protocols 2021 Nov;16(11):5287-5308
Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers.
Venkatesan A, Geng J, Kandarpa M, Wijeyesakere SJ, Bhide A, Talpaz M, Pogozheva ID, Raghavan M
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D, Haucke V
Neuron 2021 Jan 20;109(2):299-313.e9
Neuron 2021 Jan 20;109(2):299-313.e9
Local translation in nuclear condensate amyloid bodies.
Theodoridis PR, Bokros M, Marijan D, Balukoff NC, Wang D, Kirk CC, Budine TD, Goldsmith HD, Wang M, Audas TE, Lee S
Proceedings of the National Academy of Sciences of the United States of America 2021 Feb 16;118(7)
Proceedings of the National Academy of Sciences of the United States of America 2021 Feb 16;118(7)
A Novel Thienopyrimidine Analog, TPH104, Mediates Immunogenic Cell Death in Triple-Negative Breast Cancer Cells.
Tukaramrao DB, Malla S, Saraiya S, Hanely RA, Ray A, Kumari S, Raman D, Tiwari AK
Cancers 2021 Apr 18;13(8)
Cancers 2021 Apr 18;13(8)
Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.
Furlan S, Campione M, Murgia M, Mosole S, Argenton F, Volpe P, Nori A
Frontiers in neuroanatomy 2020;14:15
Frontiers in neuroanatomy 2020;14:15
Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models.
Seyedin SN, Hasibuzzaman MM, Pham V, Petronek MS, Callaghan C, Kalen AL, Mapuskar KA, Mott SL, Spitz DR, Allen BG, Caster JM
International journal of radiation oncology, biology, physics 2020 Sep 1;108(1):81-92
International journal of radiation oncology, biology, physics 2020 Sep 1;108(1):81-92
Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors.
Mei KC, Liao YP, Jiang J, Chiang M, Khazaieli M, Liu X, Wang X, Liu Q, Chang CH, Zhang X, Li J, Ji Y, Melano B, Telesca D, Xia T, Meng H, Nel AE
ACS nano 2020 Oct 27;14(10):13343-13366
ACS nano 2020 Oct 27;14(10):13343-13366
Immunomodulatory activity of IR700-labelled affibody targeting HER2.
Mączyńska J, Da Pieve C, Burley TA, Raes F, Shah A, Saczko J, Harrington KJ, Kramer-Marek G
Cell death & disease 2020 Oct 20;11(10):886
Cell death & disease 2020 Oct 20;11(10):886
Past and ongoing adaptation of human cytomegalovirus to its host.
Mozzi A, Biolatti M, Cagliani R, Forni D, Dell'Oste V, Pontremoli C, Vantaggiato C, Pozzoli U, Clerici M, Landolfo S, Sironi M
PLoS pathogens 2020 May;16(5):e1008476
PLoS pathogens 2020 May;16(5):e1008476
Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells.
Di Grazia A, Laudisi F, Di Fusco D, Franzè E, Ortenzi A, Monteleone I, Monteleone G, Stolfi C
Cancers 2020 May 21;12(5)
Cancers 2020 May 21;12(5)
Endothelial calreticulin deletion impairs endothelial function in aged mice.
Biwer LA, Askew-Page HR, Hong K, Milstein J, Johnstone SR, Macal E, Good ME, Bagher P, Sonkusare SK, Isakson BE
American journal of physiology. Heart and circulatory physiology 2020 May 1;318(5):H1041-H1048
American journal of physiology. Heart and circulatory physiology 2020 May 1;318(5):H1041-H1048
Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain.
Benfield CT, MacKenzie F, Ritzefeld M, Mazzon M, Weston S, Tate EW, Teo BH, Smith SE, Kellam P, Holmes EC, Marsh M
Life science alliance 2020 Jan;3(1)
Life science alliance 2020 Jan;3(1)
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.
Ma J, Ramachandran M, Jin C, Quijano-Rubio C, Martikainen M, Yu D, Essand M
Cell death & disease 2020 Jan 22;11(1):48
Cell death & disease 2020 Jan 22;11(1):48
Calreticulin enhances the secretory trafficking of a misfolded α-1-antitrypsin.
Mohan HM, Yang B, Dean NA, Raghavan M
The Journal of biological chemistry 2020 Dec 4;295(49):16754-16772
The Journal of biological chemistry 2020 Dec 4;295(49):16754-16772
Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.
Suzuki E, Ogawa N, Takeda TA, Nishito Y, Tanaka YK, Fujiwara T, Matsunaga M, Ueda S, Kubo N, Tsuji T, Fukunaka A, Yamazaki T, Taylor KM, Ogra Y, Kambe T
The Journal of biological chemistry 2020 Apr 24;295(17):5669-5684
The Journal of biological chemistry 2020 Apr 24;295(17):5669-5684
Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death.
Kopecka J, Godel M, Dei S, Giampietro R, Belisario DC, Akman M, Contino M, Teodori E, Riganti C
Cells 2020 Apr 22;9(4)
Cells 2020 Apr 22;9(4)
Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death.
Liu CC, Leclair P, Pedari F, Vieira H, Monajemi M, Sly LM, Reid GS, Lim CJ
Frontiers in oncology 2019;9:411
Frontiers in oncology 2019;9:411
ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases.
Anwar T, Liu X, Suntio T, Marjamäki A, Biazik J, Chan EYW, Varjosalo M, Eskelinen EL
Cells 2019 May 17;8(5)
Cells 2019 May 17;8(5)
Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity.
Rossi A, Dupaty L, Aillot L, Zhang L, Gallien C, Hallek M, Odenthal M, Adriouch S, Salvetti A, Büning H
Scientific reports 2019 Mar 6;9(1):3631
Scientific reports 2019 Mar 6;9(1):3631
The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide.
Pandya UM, Egbuta C, Abdullah Norman TM, Chiang CE, Wiersma VR, Panchal RG, Bremer E, Eggleton P, Gold LI
International journal of molecular sciences 2019 Jan 18;20(2)
International journal of molecular sciences 2019 Jan 18;20(2)
Dissociation of membrane-chromatin contacts is required for proper chromosome segregation in mitosis.
Champion L, Pawar S, Luithle N, Ungricht R, Kutay U
Molecular biology of the cell 2019 Feb 15;30(4):427-440
Molecular biology of the cell 2019 Feb 15;30(4):427-440
Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity.
Tiscione SA, Vivas O, Ginsburg KS, Bers DM, Ory DS, Santana LF, Dixon RE, Dickson EJ
The Journal of cell biology 2019 Dec 2;218(12):4141-4156
The Journal of cell biology 2019 Dec 2;218(12):4141-4156
Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models.
Takeda TA, Miyazaki S, Kobayashi M, Nishino K, Goto T, Matsunaga M, Ooi M, Shirakawa H, Tani F, Kawamura T, Komai M, Kambe T
Communications biology 2018;1:113
Communications biology 2018;1:113
Functional differences of short and long isoforms of spastin harboring missense mutation.
Plaud C, Joshi V, Kajevu N, Poüs C, Curmi PA, Burgo A
Disease models & mechanisms 2018 Sep 10;11(9)
Disease models & mechanisms 2018 Sep 10;11(9)
Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen.
Vigneron N, Ferrari V, Van den Eynde BJ, Cresswell P, Leonhardt RM
Journal of immunology (Baltimore, Md. : 1950) 2018 Oct 1;201(7):1875-1888
Journal of immunology (Baltimore, Md. : 1950) 2018 Oct 1;201(7):1875-1888
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer.
Salaroglio IC, Gazzano E, Abdullrahman A, Mungo E, Castella B, Abd-Elrahman GEFA, Massaia M, Donadelli M, Rubinstein M, Riganti C, Kopecka J
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):286
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):286
SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition.
Cieri D, Vicario M, Giacomello M, Vallese F, Filadi R, Wagner T, Pozzan T, Pizzo P, Scorrano L, Brini M, Calì T
Cell death and differentiation 2018 Jun;25(6):1131-1145
Cell death and differentiation 2018 Jun;25(6):1131-1145
Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I.
Arshad N, Cresswell P
The Journal of biological chemistry 2018 Jun 22;293(25):9555-9569
The Journal of biological chemistry 2018 Jun 22;293(25):9555-9569
Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans-Presentation.
Borrelli C, Ricci B, Vulpis E, Fionda C, Ricciardi MR, Petrucci MT, Masuelli L, Peri A, Cippitelli M, Zingoni A, Santoni A, Soriani A
Cancer immunology research 2018 Jul;6(7):860-869
Cancer immunology research 2018 Jul;6(7):860-869
Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR.
Hangen E, Cordelières FP, Petersen JD, Choquet D, Coussen F
Cell reports 2018 Jul 24;24(4):1001-1012.e3
Cell reports 2018 Jul 24;24(4):1001-1012.e3
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.
Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ
eLife 2018 Dec 13;7
eLife 2018 Dec 13;7
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.
Li L, Jiao X, D'Atri I, Ono F, Nelson R, Chan CC, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Coban Akdemir ZH, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF
PLoS genetics 2018 Aug;14(8):e1007504
PLoS genetics 2018 Aug;14(8):e1007504
Nesprin-2 Interacts with Condensin Component SMC2.
Xing X, Mroß C, Hao L, Munck M, Herzog A, Mohr C, Unnikannan CP, Kelkar P, Noegel AA, Eichinger L, Neumann S
International journal of cell biology 2017;2017:8607532
International journal of cell biology 2017;2017:8607532
Association of calreticulin expression with disease activity and organ damage in systemic lupus erythematosus patients.
Wang Y, Xie J, Liu Z, Fu H, Huo Q, Gu Y, Liu Y
Experimental and therapeutic medicine 2017 May;13(5):2577-2583
Experimental and therapeutic medicine 2017 May;13(5):2577-2583
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways.
Granato M, Rizzello C, Gilardini Montani MS, Cuomo L, Vitillo M, Santarelli R, Gonnella R, D'Orazi G, Faggioni A, Cirone M
The Journal of nutritional biochemistry 2017 Mar;41:124-136
The Journal of nutritional biochemistry 2017 Mar;41:124-136
A novel approach to assess the ubiquitin-fold modifier 1-system in cells.
Ishimura R, Obata M, Kageyama S, Daniel J, Tanaka K, Komatsu M
FEBS letters 2017 Jan;591(1):196-204
FEBS letters 2017 Jan;591(1):196-204
FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.
Doghman-Bouguerra M, Granatiero V, Sbiera S, Sbiera I, Lacas-Gervais S, Brau F, Fassnacht M, Rizzuto R, Lalli E
EMBO reports 2016 Sep;17(9):1264-80
EMBO reports 2016 Sep;17(9):1264-80
Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants.
Greenwood EJ, Matheson NJ, Wals K, van den Boomen DJ, Antrobus R, Williamson JC, Lehner PJ
eLife 2016 Sep 30;5
eLife 2016 Sep 30;5
Characterization of the ER-Targeted Low Affinity Ca(2+) Probe D4ER.
Greotti E, Wong A, Pozzan T, Pendin D, Pizzo P
Sensors (Basel, Switzerland) 2016 Sep 2;16(9)
Sensors (Basel, Switzerland) 2016 Sep 2;16(9)
VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation.
Shih YT, Hsueh YP
Nature communications 2016 Mar 17;7:11020
Nature communications 2016 Mar 17;7:11020
α-Integrin expression and function modulates presentation of cell surface calreticulin.
Liu CC, Leclair P, Monajemi M, Sly LM, Reid GS, Lim CJ
Cell death & disease 2016 Jun 16;7(6):e2268
Cell death & disease 2016 Jun 16;7(6):e2268
Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.
Mosca B, Eckhardt J, Bergamelli L, Treves S, Bongianino R, De Negri M, Priori SG, Protasi F, Zorzato F
The Journal of biological chemistry 2016 Jul 8;291(28):14555-65
The Journal of biological chemistry 2016 Jul 8;291(28):14555-65
Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology.
Ruegsegger C, Stucki DM, Steiner S, Angliker N, Radecke J, Keller E, Zuber B, Rüegg MA, Saxena S
Neuron 2016 Jan 6;89(1):129-46
Neuron 2016 Jan 6;89(1):129-46
A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice.
Tagliamonte M, Petrizzo A, Napolitano M, Luciano A, Rea D, Barbieri A, Arra C, Maiolino P, Tornesello M, Ciliberto G, Buonaguro FM, Buonaguro L
Journal of translational medicine 2016 Feb 24;14:58
Journal of translational medicine 2016 Feb 24;14:58
A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.
Matsuno H, Ohi K, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Yano-Umeda S, Saneyoshi T, Takeda M, Hayashi Y
PloS one 2015;10(3):e0116319
PloS one 2015;10(3):e0116319
Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected Primary Fibroblasts.
Williamson CD, Wong DS, Bozidis P, Zhang A, Colberg-Poley AM
Current protocols in cell biology 2015 Sep 1;68:3.27.1-3.27.33
Current protocols in cell biology 2015 Sep 1;68:3.27.1-3.27.33
Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression.
Granato M, Gilardini Montani MS, Filardi M, Faggioni A, Cirone M
Oncotarget 2015 Oct 6;6(30):29543-54
Oncotarget 2015 Oct 6;6(30):29543-54
Regulation of calreticulin-major histocompatibility complex (MHC) class I interactions by ATP.
Wijeyesakere SJ, Gagnon JK, Arora K, Brooks CL 3rd, Raghavan M
Proceedings of the National Academy of Sciences of the United States of America 2015 Oct 13;112(41):E5608-17
Proceedings of the National Academy of Sciences of the United States of America 2015 Oct 13;112(41):E5608-17
A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.
Parkinson MD, Piper SC, Bright NA, Evans JL, Boname JM, Bowers K, Lehner PJ, Luzio JP
The Biochemical journal 2015 Oct 1;471(1):79-88
The Biochemical journal 2015 Oct 1;471(1):79-88
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.
Tafaleng EN, Chakraborty S, Han B, Hale P, Wu W, Soto-Gutierrez A, Feghali-Bostwick CA, Wilson AA, Kotton DN, Nagaya M, Strom SC, Roy-Chowdhury J, Stolz DB, Perlmutter DH, Fox IJ
Hepatology (Baltimore, Md.) 2015 Jul;62(1):147-57
Hepatology (Baltimore, Md.) 2015 Jul;62(1):147-57
Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice.
Bernard-Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B
Neurobiology of disease 2015 Jan;73:130-6
Neurobiology of disease 2015 Jan;73:130-6
Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses.
Turpin J, Journo C, Ko NL, Sinet F, Carpentier A, Galioot A, Edwards D, Vandamme AM, Gazzolo L, Duc Dodon M, Gessain A, Kashanchi F, Balansard I, Lacoste R, Mahieux R
Journal of virology 2015 Jan 15;89(2):931-51
Journal of virology 2015 Jan 15;89(2):931-51
Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.
Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, Roos A, Troost D, Schneider BL, Weis J, Saxena S
Nature neuroscience 2015 Feb;18(2):227-38
Nature neuroscience 2015 Feb;18(2):227-38
Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.
Blin S, Chatelain FC, Feliciangeli S, Kang D, Lesage F, Bichet D
The Journal of biological chemistry 2014 Oct 10;289(41):28202-12
The Journal of biological chemistry 2014 Oct 10;289(41):28202-12
Calreticulin promotes angiogenesis via activating nitric oxide signalling pathway in rheumatoid arthritis.
Ding H, Hong C, Wang Y, Liu J, Zhang N, Shen C, Wei W, Zheng F
Clinical and experimental immunology 2014 Nov;178(2):236-44
Clinical and experimental immunology 2014 Nov;178(2):236-44
Intracellular trafficking of the human cytomegalovirus-encoded 7-trans-membrane protein homologs pUS27 and pUL78 during viral infection: a comparative analysis.
Niemann I, Reichel A, Stamminger T
Viruses 2014 Feb 10;6(2):661-82
Viruses 2014 Feb 10;6(2):661-82
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Cherepanova NA, Shrimal S, Gilmore R
The Journal of cell biology 2014 Aug 18;206(4):525-39
The Journal of cell biology 2014 Aug 18;206(4):525-39
ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays.
Joensuu M, Belevich I, Rämö O, Nevzorov I, Vihinen H, Puhka M, Witkos TM, Lowe M, Vartiainen MK, Jokitalo E
Molecular biology of the cell 2014 Apr;25(7):1111-26
Molecular biology of the cell 2014 Apr;25(7):1111-26
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells.
Cirone M, Garufi A, Di Renzo L, Granato M, Faggioni A, D'Orazi G
Oncoimmunology 2013 Sep 1;2(9):e26198
Oncoimmunology 2013 Sep 1;2(9):e26198
The membrane-proximal KXGFFKR motif of α-integrin mediates chemoresistance.
Liu CC, Leclair P, Yap SQ, Lim CJ
Molecular and cellular biology 2013 Nov;33(21):4334-45
Molecular and cellular biology 2013 Nov;33(21):4334-45
Serum levels of calreticulin in correlation with disease activity in patients with rheumatoid arthritis.
Ni M, Wei W, Wang Y, Zhang N, Ding H, Shen C, Zheng F
Journal of clinical immunology 2013 Jul;33(5):947-53
Journal of clinical immunology 2013 Jul;33(5):947-53
Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.
Journo C, Bonnet A, Favre-Bonvin A, Turpin J, Vinera J, Côté E, Chevalier SA, Kfoury Y, Bazarbachi A, Pique C, Mahieux R
Journal of virology 2013 Jan;87(2):1123-36
Journal of virology 2013 Jan;87(2):1123-36
FRET-based sensor analysis reveals caveolae are spatially distinct Ca2+ stores in endothelial cells.
Isshiki M, Nishimoto M, Mizuno R, Fujita T
Cell calcium 2013 Dec;54(6):395-403
Cell calcium 2013 Dec;54(6):395-403
Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane.
Chatelain FC, Bichet D, Feliciangeli S, Larroque MM, Braud VM, Douguet D, Lesage F
The Journal of biological chemistry 2013 Dec 6;288(49):35081-92
The Journal of biological chemistry 2013 Dec 6;288(49):35081-92
Gas1 interferes with AβPP trafficking by facilitating the accumulation of immature AβPP in endoplasmic reticulum-associated raft subdomains.
Chapuis J, Vingtdeux V, Capiralla H, Davies P, Marambaud P
Journal of Alzheimer's disease : JAD 2012;28(1):127-35
Journal of Alzheimer's disease : JAD 2012;28(1):127-35
Cell-Type-Specific Effects of Silibinin on Vitamin D-Induced Differentiation of Acute Myeloid Leukemia Cells Are Associated with Differential Modulation of RXRα Levels.
Wassermann R, Novik V, Danilenko M
Leukemia research and treatment 2012;2012:401784
Leukemia research and treatment 2012;2012:401784
Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.
Gabillet J, Millet A, Pederzoli-Ribeil M, Tacnet-Delorme P, Guillevin L, Mouthon L, Frachet P, Witko-Sarsat V
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 1;189(5):2574-83
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 1;189(5):2574-83
Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Ohbayashi N, Maruta Y, Ishida M, Fukuda M
Journal of cell science 2012 Mar 15;125(Pt 6):1508-18
Journal of cell science 2012 Mar 15;125(Pt 6):1508-18
Some fine-structural findings on the thyroid gland in Apc1638T/1638T mice that express a C-terminus lacking truncated Apc.
Yokoyama A, Nomura R, Kurosumi M, Shimomura A, Onouchi T, Iizuka-Kogo A, Smits R, Fodde R, Itoh M, Senda T
Medical molecular morphology 2012 Jun;45(3):161-7
Medical molecular morphology 2012 Jun;45(3):161-7
A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles.
Yoshii K, Igarashi M, Ichii O, Yokozawa K, Ito K, Kariwa H, Takashima I
The Journal of general virology 2012 Jan;93(Pt 1):27-38
The Journal of general virology 2012 Jan;93(Pt 1):27-38
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle.
Starr T, Child R, Wehrly TD, Hansen B, Hwang S, López-Otin C, Virgin HW, Celli J
Cell host & microbe 2012 Jan 19;11(1):33-45
Cell host & microbe 2012 Jan 19;11(1):33-45
Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms.
Patil H, Guruju MR, Cho KI, Yi H, Orry A, Kim H, Ferreira PA
Biology open 2012 Feb 15;1(2):140-60
Biology open 2012 Feb 15;1(2):140-60
Reduced calreticulin levels link endoplasmic reticulum stress and Fas-triggered cell death in motoneurons vulnerable to ALS.
Bernard-Marissal N, Moumen A, Sunyach C, Pellegrino C, Dudley K, Henderson CE, Raoul C, Pettmann B
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Apr 4;32(14):4901-12
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Apr 4;32(14):4901-12
Measurement of activation of the endoplasmic reticulum stress response in autoimmune myositis.
Alger HM, Rayavarapu S, Nagaraju K
Methods in enzymology 2011;489:207-25
Methods in enzymology 2011;489:207-25
Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism.
Maruyama S, Shibata R, Ohashi K, Ohashi T, Daida H, Walsh K, Murohara T, Ouchi N
The Journal of biological chemistry 2011 Sep 16;286(37):32790-800
The Journal of biological chemistry 2011 Sep 16;286(37):32790-800
Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection.
Zhang A, Williamson CD, Wong DS, Bullough MD, Brown KJ, Hathout Y, Colberg-Poley AM
Molecular & cellular proteomics : MCP 2011 Oct;10(10):M111.009936
Molecular & cellular proteomics : MCP 2011 Oct;10(10):M111.009936
Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis.
Kopil CM, Vais H, Cheung KH, Siebert AP, Mak DD, Foskett JK, Neumar RW
The Journal of biological chemistry 2011 Oct 14;286(41):35998-36010
The Journal of biological chemistry 2011 Oct 14;286(41):35998-36010
Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus.
Thorne C, Eccles RL, Coulson JM, Urbé S, Clague MJ
Traffic (Copenhagen, Denmark) 2011 Nov;12(11):1563-74
Traffic (Copenhagen, Denmark) 2011 Nov;12(11):1563-74
Calreticulin-2 is localized in the lumen of the endoplasmic reticulum but is not a Ca2+ -binding protein.
Nomura R, Orii M, Senda T
Histochemistry and cell biology 2011 Jun;135(6):531-8
Histochemistry and cell biology 2011 Jun;135(6):531-8
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.
Kopecka J, Campia I, Brusa D, Doublier S, Matera L, Ghigo D, Bosia A, Riganti C
Journal of cellular and molecular medicine 2011 Jul;15(7):1492-504
Journal of cellular and molecular medicine 2011 Jul;15(7):1492-504
Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase.
Andre B, Duterme C, Van Moer K, Mertens-Strijthagen J, Jadot M, Flamion B
Biochemical and biophysical research communications 2011 Jul 22;411(1):175-9
Biochemical and biophysical research communications 2011 Jul 22;411(1):175-9
Loss of membrane targeting of Vangl proteins causes neural tube defects.
Iliescu A, Gravel M, Horth C, Kibar Z, Gros P
Biochemistry 2011 Feb 8;50(5):795-804
Biochemistry 2011 Feb 8;50(5):795-804
Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells.
Cattaneo M, Lotti LV, Martino S, Alessio M, Conti A, Bachi A, Mariani-Costantini R, Biunno I
PloS one 2011 Feb 17;6(2):e17206
PloS one 2011 Feb 17;6(2):e17206
'IntraCell' plugin for assessment of intracellular localization of nano-delivery systems and their targeting to the individual organelles.
Sneh-Edri H, Stepensky D
Biochemical and biophysical research communications 2011 Feb 11;405(2):228-33
Biochemical and biophysical research communications 2011 Feb 11;405(2):228-33
The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells.
Bobilev I, Novik V, Levi I, Shpilberg O, Levy J, Sharoni Y, Studzinski GP, Danilenko M
Cancer biology & therapy 2011 Feb 1;11(3):317-29
Cancer biology & therapy 2011 Feb 1;11(3):317-29
The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function.
Yokoyama A, Nomura R, Kurosumi M, Shimomura A, Onouchi T, Iizuka-Kogo A, Smits R, Oda N, Fodde R, Itoh M, Senda T
Medical molecular morphology 2011 Dec;44(4):207-12
Medical molecular morphology 2011 Dec;44(4):207-12
Calreticulin binds to gentamicin and reduces drug-induced ototoxicity.
Karasawa T, Wang Q, David LL, Steyger PS
Toxicological sciences : an official journal of the Society of Toxicology 2011 Dec;124(2):378-87
Toxicological sciences : an official journal of the Society of Toxicology 2011 Dec;124(2):378-87
Role of Rab1b in COPII dynamics and function.
Slavin I, García IA, Monetta P, Martinez H, Romero N, Alvarez C
European journal of cell biology 2011 Apr;90(4):301-11
European journal of cell biology 2011 Apr;90(4):301-11
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.
Pesakhov S, Khanin M, Studzinski GP, Danilenko M
Nutrition and cancer 2010;62(6):811-24
Nutrition and cancer 2010;62(6):811-24
Ero1alpha requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM).
Gilady SY, Bui M, Lynes EM, Benson MD, Watts R, Vance JE, Simmen T
Cell stress & chaperones 2010 Sep;15(5):619-29
Cell stress & chaperones 2010 Sep;15(5):619-29
A mechanism of release of calreticulin from cells during apoptosis.
Tarr JM, Young PJ, Morse R, Shaw DJ, Haigh R, Petrov PG, Johnson SJ, Winyard PG, Eggleton P
Journal of molecular biology 2010 Sep 3;401(5):799-812
Journal of molecular biology 2010 Sep 3;401(5):799-812
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
de Waard MC, van der Pluijm I, Zuiderveen Borgesius N, Comley LH, Haasdijk ED, Rijksen Y, Ridwan Y, Zondag G, Hoeijmakers JH, Elgersma Y, Gillingwater TH, Jaarsma D
Acta neuropathologica 2010 Oct;120(4):461-75
Acta neuropathologica 2010 Oct;120(4):461-75
The sodium/proton exchanger NHE8 regulates late endosomal morphology and function.
Lawrence SP, Bright NA, Luzio JP, Bowers K
Molecular biology of the cell 2010 Oct 15;21(20):3540-51
Molecular biology of the cell 2010 Oct 15;21(20):3540-51
Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease.
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, Liu X, Sun L, Lv P, Gao XM
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4561-9
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4561-9
Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils.
Mollinedo F, Janssen H, de la Iglesia-Vicente J, Villa-Pulgarin JA, Calafat J
The Journal of biological chemistry 2010 Nov 5;285(45):34528-36
The Journal of biological chemistry 2010 Nov 5;285(45):34528-36
Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).
Wang X, Gocek E, Novik V, Harrison JS, Danilenko M, Studzinski GP
Cell cycle (Georgetown, Tex.) 2010 Nov 15;9(22):4542-51
Cell cycle (Georgetown, Tex.) 2010 Nov 15;9(22):4542-51
Dysferlin overexpression in skeletal muscle produces a progressive myopathy.
Glover LE, Newton K, Krishnan G, Bronson R, Boyle A, Krivickas LS, Brown RH Jr
Annals of neurology 2010 Mar;67(3):384-93
Annals of neurology 2010 Mar;67(3):384-93
Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.
Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG
The Journal of biological chemistry 2010 Jan 22;285(4):2796-806
The Journal of biological chemistry 2010 Jan 22;285(4):2796-806
Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture.
Kii I, Nishiyama T, Li M, Matsumoto K, Saito M, Amizuka N, Kudo A
The Journal of biological chemistry 2010 Jan 15;285(3):2028-39
The Journal of biological chemistry 2010 Jan 15;285(3):2028-39
Association of HTLV Tax proteins with TAK1-binding protein 2 and RelA in calreticulin-containing cytoplasmic structures participates in Tax-mediated NF-κB activation.
Avesani F, Romanelli MG, Turci M, Di Gennaro G, Sampaio C, Bidoia C, Bertazzoni U, Bex F
Virology 2010 Dec 5;408(1):39-48
Virology 2010 Dec 5;408(1):39-48
Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse.
Gravel M, Iliescu A, Horth C, Apuzzo S, Gros P
Biochemistry 2010 Apr 27;49(16):3445-55
Biochemistry 2010 Apr 27;49(16):3445-55
An arginine stretch limits ADAM10 exit from the endoplasmic reticulum.
Marcello E, Gardoni F, Di Luca M, Pérez-Otaño I
The Journal of biological chemistry 2010 Apr 2;285(14):10376-84
The Journal of biological chemistry 2010 Apr 2;285(14):10376-84
Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation.
Vigneron N, Peaper DR, Leonhardt RM, Cresswell P
European journal of immunology 2009 Sep;39(9):2371-6
European journal of immunology 2009 Sep;39(9):2371-6
Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system.
Linnewiel K, Ernst H, Caris-Veyrat C, Ben-Dor A, Kampf A, Salman H, Danilenko M, Levy J, Sharoni Y
Free radical biology & medicine 2009 Sep 1;47(5):659-67
Free radical biology & medicine 2009 Sep 1;47(5):659-67
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells.
De Boo S, Kopecka J, Brusa D, Gazzano E, Matera L, Ghigo D, Bosia A, Riganti C
Molecular cancer 2009 Nov 19;8:108
Molecular cancer 2009 Nov 19;8:108
Differential cell death regulation between adult-unloaded and aged rat soleus muscle.
Ogata T, Machida S, Oishi Y, Higuchi M, Muraoka I
Mechanisms of ageing and development 2009 May;130(5):328-36
Mechanisms of ageing and development 2009 May;130(5):328-36
Transcriptome and proteome analysis of osteocytes treated with nitrogen-containing bisphosphonates.
Bivi N, Bereszczak JZ, Romanello M, Zeef LA, Delneri D, Quadrifoglio F, Moro L, Brancia FL, Tell G
Journal of proteome research 2009 Mar;8(3):1131-42
Journal of proteome research 2009 Mar;8(3):1131-42
Chronic stress elicits prolonged activation of alpha-MSH secretion and subsequent degeneration of melanotroph.
Ogawa T, Shishioh-Ikejima N, Konishi H, Makino T, Sei H, Kiryu-Seo S, Tanaka M, Watanabe Y, Kiyama H
Journal of neurochemistry 2009 Jun;109(5):1389-99
Journal of neurochemistry 2009 Jun;109(5):1389-99
A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles.
Ninio S, Celli J, Roy CR
PLoS pathogens 2009 Jan;5(1):e1000278
PLoS pathogens 2009 Jan;5(1):e1000278
The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival.
Vafiadaki E, Arvanitis DA, Pagakis SN, Papalouka V, Sanoudou D, Kontrogianni-Konstantopoulos A, Kranias EG
Molecular biology of the cell 2009 Jan;20(1):306-18
Molecular biology of the cell 2009 Jan;20(1):306-18
Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules.
Howe C, Garstka M, Al-Balushi M, Ghanem E, Antoniou AN, Fritzsche S, Jankevicius G, Kontouli N, Schneeweiss C, Williams A, Elliott T, Springer S
The EMBO journal 2009 Dec 2;28(23):3730-44
The EMBO journal 2009 Dec 2;28(23):3730-44
Functional characterization of two secreted SEL1L isoforms capable of exporting unassembled substrate.
Cattaneo M, Lotti LV, Martino S, Cardano M, Orlandi R, Mariani-Costantini R, Biunno I
The Journal of biological chemistry 2009 Apr 24;284(17):11405-15
The Journal of biological chemistry 2009 Apr 24;284(17):11405-15
Intracellular localization of Brucella abortus and Francisella tularensis in primary murine macrophages.
Celli J
Methods in molecular biology (Clifton, N.J.) 2008;431:133-45
Methods in molecular biology (Clifton, N.J.) 2008;431:133-45
Intracellular localization of Brucella abortus and Francisella tularensis in primary murine macrophages.
Celli J
Methods in molecular biology (Clifton, N.J.) 2008;431:133-45
Methods in molecular biology (Clifton, N.J.) 2008;431:133-45
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X.
Nathan JA, Sengupta S, Wood SA, Admon A, Markson G, Sanderson C, Lehner PJ
Traffic (Copenhagen, Denmark) 2008 Jul;9(7):1130-45
Traffic (Copenhagen, Denmark) 2008 Jul;9(7):1130-45
The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading.
Peaper DR, Cresswell P
Proceedings of the National Academy of Sciences of the United States of America 2008 Jul 29;105(30):10477-82
Proceedings of the National Academy of Sciences of the United States of America 2008 Jul 29;105(30):10477-82
A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein.
Pearse BR, Gabriel L, Wang N, Hebert DN
The Journal of cell biology 2008 Apr 21;181(2):309-20
The Journal of cell biology 2008 Apr 21;181(2):309-20
Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.
Teuling E, Ahmed S, Haasdijk E, Demmers J, Steinmetz MO, Akhmanova A, Jaarsma D, Hoogenraad CC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Sep 5;27(36):9801-15
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Sep 5;27(36):9801-15
Impact of two novel mutations on the structure and function of human myeloperoxidase.
Goedken M, McCormick S, Leidal KG, Suzuki K, Kameoka Y, Astern JM, Huang M, Cherkasov A, Nauseef WM
The Journal of biological chemistry 2007 Sep 21;282(38):27994-8003
The Journal of biological chemistry 2007 Sep 21;282(38):27994-8003
Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library.
Mohrlüder J, Stangler T, Hoffmann Y, Wiesehan K, Mataruga A, Willbold D
The FEBS journal 2007 Nov;274(21):5543-55
The FEBS journal 2007 Nov;274(21):5543-55
The rheumatoid arthritis shared epitope triggers innate immune signaling via cell surface calreticulin.
Ling S, Pi X, Holoshitz J
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 1;179(9):6359-67
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 1;179(9):6359-67
Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration.
Proux-Gillardeaux V, Raposo G, Irinopoulou T, Galli T
Biology of the cell 2007 May;99(5):261-71
Biology of the cell 2007 May;99(5):261-71
Post-translational arginylation of calreticulin: a new isospecies of calreticulin component of stress granules.
Decca MB, Carpio MA, Bosc C, Galiano MR, Job D, Andrieux A, Hallak ME
The Journal of biological chemistry 2007 Mar 16;282(11):8237-45
The Journal of biological chemistry 2007 Mar 16;282(11):8237-45
Influence of Ki-ras-driven oncogenic transformation on the protein network of murine fibroblasts.
Recktenwald CV, Mendler S, Lichtenfels R, Kellner R, Seliger B
Proteomics 2007 Feb;7(3):385-98
Proteomics 2007 Feb;7(3):385-98
Isolation of endoplasmic reticulum, mitochondria, and mitochondria-associated membrane fractions from transfected cells and from human cytomegalovirus-infected primary fibroblasts.
Bozidis P, Williamson CD, Colberg-Poley AM
Current protocols in cell biology 2007 Dec;Chapter 3:Unit 3.27
Current protocols in cell biology 2007 Dec;Chapter 3:Unit 3.27
Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer.
Wearsch PA, Cresswell P
Nature immunology 2007 Aug;8(8):873-81
Nature immunology 2007 Aug;8(8):873-81
Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP.
Mimura N, Hamada H, Kashio M, Jin H, Toyama Y, Kimura K, Iida M, Goto S, Saisho H, Toshimori K, Koseki H, Aoe T
Cell death and differentiation 2007 Aug;14(8):1475-85
Cell death and differentiation 2007 Aug;14(8):1475-85
Lycopene and other carotenoids inhibit estrogenic activity of 17beta-estradiol and genistein in cancer cells.
Hirsch K, Atzmon A, Danilenko M, Levy J, Sharoni Y
Breast cancer research and treatment 2007 Aug;104(2):221-30
Breast cancer research and treatment 2007 Aug;104(2):221-30
Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.
Sun H, Liu X, Xiong Q, Shikano S, Li M
The Journal of biological chemistry 2006 Mar 3;281(9):5877-84
The Journal of biological chemistry 2006 Mar 3;281(9):5877-84
Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera.
Chignard N, Shang S, Wang H, Marrero J, Bréchot C, Hanash S, Beretta L
Gastroenterology 2006 Jun;130(7):2010-22
Gastroenterology 2006 Jun;130(7):2010-22
Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites.
Halbach A, Landgraf C, Lorenzen S, Rosenkranz K, Volkmer-Engert R, Erdmann R, Rottensteiner H
Journal of cell science 2006 Jun 15;119(Pt 12):2508-17
Journal of cell science 2006 Jun 15;119(Pt 12):2508-17
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.
Bowers K, Piper SC, Edeling MA, Gray SR, Owen DJ, Lehner PJ, Luzio JP
The Journal of biological chemistry 2006 Feb 24;281(8):5094-105
The Journal of biological chemistry 2006 Feb 24;281(8):5094-105
Androgen-regulated formation and degradation of gap junctions in androgen-responsive human prostate cancer cells.
Mitra S, Annamalai L, Chakraborty S, Johnson K, Song XH, Batra SK, Mehta PP
Molecular biology of the cell 2006 Dec;17(12):5400-16
Molecular biology of the cell 2006 Dec;17(12):5400-16
Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal.
Hodson CA, Ambrogi IG, Scott RO, Mohler PJ, Milgram SL
Traffic (Copenhagen, Denmark) 2006 Apr;7(4):456-64
Traffic (Copenhagen, Denmark) 2006 Apr;7(4):456-64
Effects of aging on Ca2+ signaling in murine mesenteric arterial smooth muscle cells.
del Corsso C, Ostrovskaya O, McAllister CE, Murray K, Hatton WJ, Gurney AM, Spencer NJ, Wilson SM
Mechanisms of ageing and development 2006 Apr;127(4):315-23
Mechanisms of ageing and development 2006 Apr;127(4):315-23
Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells.
Snapp EL, Sharma A, Lippincott-Schwartz J, Hegde RS
Proceedings of the National Academy of Sciences of the United States of America 2006 Apr 25;103(17):6536-41
Proceedings of the National Academy of Sciences of the United States of America 2006 Apr 25;103(17):6536-41
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.
Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio JP, Lehner PJ
The EMBO journal 2006 Apr 19;25(8):1635-45
The EMBO journal 2006 Apr 19;25(8):1635-45
Mucin granules are in close contact with tubular elements of the endoplasmic reticulum.
Perez-Vilar J, Ribeiro CM, Salmon WC, Mabolo R, Boucher RC
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005 Oct;53(10):1305-9
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005 Oct;53(10):1305-9
Different approaches for assaying melanosome transfer.
Berens W, Van Den Bossche K, Yoon TJ, Westbroek W, Valencia JC, Out CJ, Marie Naeyaert J, Hearing VJ, Lambert J
Pigment cell research 2005 Oct;18(5):370-81
Pigment cell research 2005 Oct;18(5):370-81
C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors.
Coblitz B, Shikano S, Wu M, Gabelli SB, Cockrell LM, Spieker M, Hanyu Y, Fu H, Amzel LM, Li M
The Journal of biological chemistry 2005 Oct 28;280(43):36263-72
The Journal of biological chemistry 2005 Oct 28;280(43):36263-72
MAP-1 is a mitochondrial effector of Bax.
Tan KO, Fu NY, Sukumaran SK, Chan SL, Kang JH, Poon KL, Chen BS, Yu VC
Proceedings of the National Academy of Sciences of the United States of America 2005 Oct 11;102(41):14623-8
Proceedings of the National Academy of Sciences of the United States of America 2005 Oct 11;102(41):14623-8
Mitochondrially targeted p53 has tumor suppressor activities in vivo.
Talos F, Petrenko O, Mena P, Moll UM
Cancer research 2005 Nov 1;65(21):9971-81
Cancer research 2005 Nov 1;65(21):9971-81
TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination.
Wu CJ, Conze DB, Li X, Ying SX, Hanover JA, Ashwell JD
The EMBO journal 2005 May 18;24(10):1886-98
The EMBO journal 2005 May 18;24(10):1886-98
Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
Yoshida Y, Adachi E, Fukiya K, Iwai K, Tanaka K
EMBO reports 2005 Mar;6(3):239-44
EMBO reports 2005 Mar;6(3):239-44
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
The Journal of biological chemistry 2005 Mar 18;280(11):10305-17
The Journal of biological chemistry 2005 Mar 18;280(11):10305-17
Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia.
Ribeiro CM, Paradiso AM, Carew MA, Shears SB, Boucher RC
The Journal of biological chemistry 2005 Mar 18;280(11):10202-9
The Journal of biological chemistry 2005 Mar 18;280(11):10202-9
Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival.
Arellano-Reynoso B, Lapaque N, Salcedo S, Briones G, Ciocchini AE, Ugalde R, Moreno E, Moriyón I, Gorvel JP
Nature immunology 2005 Jun;6(6):618-25
Nature immunology 2005 Jun;6(6):618-25
The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells.
Brini M, Miuzzo M, Pierobon N, Negro A, Sorgato MC
Molecular biology of the cell 2005 Jun;16(6):2799-808
Molecular biology of the cell 2005 Jun;16(6):2799-808
Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells.
Chen D, Texada DE, Duggan C, Liang C, Reden TB, Kooragayala LM, Langford MP
The Journal of biological chemistry 2005 Jun 10;280(23):22425-36
The Journal of biological chemistry 2005 Jun 10;280(23):22425-36
Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.
Vance BA, Harley PH, Backlund PS, Ward Y, Phelps TL, Gress RE
Archives of biochemistry and biophysics 2005 Jun 1;438(1):11-20
Archives of biochemistry and biophysics 2005 Jun 1;438(1):11-20
Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.
Garwicz D, Lennartsson A, Jacobsen SE, Gullberg U, Lindmark A
Haematologica 2005 Jan;90(1):38-44
Haematologica 2005 Jan;90(1):38-44
Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2.
Stillemark-Billton P, Beck C, Borén J, Olofsson SO
Journal of lipid research 2005 Jan;46(1):104-14
Journal of lipid research 2005 Jan;46(1):104-14
Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.
Suzuki T, Ishihara K, Migaki H, Matsuura W, Kohda A, Okumura K, Nagao M, Yamaguchi-Iwai Y, Kambe T
The Journal of biological chemistry 2005 Jan 7;280(1):637-43
The Journal of biological chemistry 2005 Jan 7;280(1):637-43
The cotranslational maturation of the type I membrane glycoprotein tyrosinase: the heat shock protein 70 system hands off to the lectin-based chaperone system.
Wang N, Daniels R, Hebert DN
Molecular biology of the cell 2005 Aug;16(8):3740-52
Molecular biology of the cell 2005 Aug;16(8):3740-52
Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide.
Cogoi S, Codognotto A, Rapozzi V, Meeuwenoord N, van der Marel G, Xodo LE
Biochemistry 2005 Aug 9;44(31):10510-9
Biochemistry 2005 Aug 9;44(31):10510-9
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking.
Nakamura N, Fukuda H, Kato A, Hirose S
Molecular biology of the cell 2005 Apr;16(4):1696-710
Molecular biology of the cell 2005 Apr;16(4):1696-710
Newly synthesized hepatitis C virus replicon RNA is protected from nuclease activity by a protease-sensitive factor(s).
Yang G, Pevear DC, Collett MS, Chunduru S, Young DC, Benetatos C, Jordan R
Journal of virology 2004 Sep;78(18):10202-5
Journal of virology 2004 Sep;78(18):10202-5
HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RII alpha regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling.
Demaugre F, Philippe Y, Sar S, Pileire B, Christa L, Lasserre C, Brechot C
European journal of biochemistry 2004 Oct;271(19):3812-20
European journal of biochemistry 2004 Oct;271(19):3812-20
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
de Jong AS, Melchers WJ, Glaudemans DH, Willems PH, van Kuppeveld FJ
The Journal of biological chemistry 2004 May 7;279(19):19924-35
The Journal of biological chemistry 2004 May 7;279(19):19924-35
Activity-dependent expression of inositol 1,4,5-trisphosphate receptor type 1 in hippocampal neurons.
Cai W, Hisatsune C, Nakamura K, Nakamura T, Inoue T, Mikoshiba K
The Journal of biological chemistry 2004 May 28;279(22):23691-8
The Journal of biological chemistry 2004 May 28;279(22):23691-8
Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation.
Barker TH, Pallero MA, MacEwen MW, Tilden SG, Woods A, Murphy-Ullrich JE, Hagood JS
The Journal of biological chemistry 2004 May 28;279(22):23510-6
The Journal of biological chemistry 2004 May 28;279(22):23510-6
Membrane fusion of secretory vesicles of the sea urchin egg in the absence of NSF.
Whalley T, Timmers K, Coorssen J, Bezrukov L, Kingsley DH, Zimmerberg J
Journal of cell science 2004 May 1;117(Pt 11):2345-56
Journal of cell science 2004 May 1;117(Pt 11):2345-56
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.
Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB
Molecular microbiology 2004 Mar;51(5):1233-49
Molecular microbiology 2004 Mar;51(5):1233-49
N-glycosylation is crucial for folding, trafficking, and stability of human tripeptidyl-peptidase I.
Wujek P, Kida E, Walus M, Wisniewski KE, Golabek AA
The Journal of biological chemistry 2004 Mar 26;279(13):12827-39
The Journal of biological chemistry 2004 Mar 26;279(13):12827-39
Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.
Hattori M, Suzuki AZ, Higo T, Miyauchi H, Michikawa T, Nakamura T, Inoue T, Mikoshiba K
The Journal of biological chemistry 2004 Mar 19;279(12):11967-75
The Journal of biological chemistry 2004 Mar 19;279(12):11967-75
Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.
Gonzalez-Alegre P, Paulson HL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Mar 17;24(11):2593-601
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Mar 17;24(11):2593-601
Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.
Wearsch PA, Jakob CA, Vallin A, Dwek RA, Rudd PM, Cresswell P
The Journal of biological chemistry 2004 Jun 11;279(24):25112-21
The Journal of biological chemistry 2004 Jun 11;279(24):25112-21
A new tool for plant cell biology: in vivo antibody uptake in plant protoplasts.
Brière C, Barthou H, Petitprez M
Plant cell reports 2004 Jul;22(12):878-84
Plant cell reports 2004 Jul;22(12):878-84
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.
Zhu H, Larade K, Jackson TA, Xie J, Ladoux A, Acker H, Berchner-Pfannschmidt U, Fandrey J, Cross AR, Lukat-Rodgers GS, Rodgers KR, Bunn HF
The Journal of biological chemistry 2004 Jul 16;279(29):30316-25
The Journal of biological chemistry 2004 Jul 16;279(29):30316-25
Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle.
Glover L, Heffron JJ, Ohlendieck K
Journal of applied physiology (Bethesda, Md. : 1985) 2004 Jan;96(1):11-8
Journal of applied physiology (Bethesda, Md. : 1985) 2004 Jan;96(1):11-8
Endoplasmic reticulum stress and unfolded protein response in inclusion body myositis muscle.
Vattemi G, Engel WK, McFerrin J, Askanas V
The American journal of pathology 2004 Jan;164(1):1-7
The American journal of pathology 2004 Jan;164(1):1-7
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation.
Erster S, Mihara M, Kim RH, Petrenko O, Moll UM
Molecular and cellular biology 2004 Aug;24(15):6728-41
Molecular and cellular biology 2004 Aug;24(15):6728-41
An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.
Hong SH, Misek DE, Wang H, Puravs E, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM
Cancer research 2004 Aug 1;64(15):5504-10
Cancer research 2004 Aug 1;64(15):5504-10
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.
Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S
Nature 2003 Sep 25;425(6956):397-402
Nature 2003 Sep 25;425(6956):397-402
Human T-cell lymphotropic virus type 1 p12I enhances interleukin-2 production during T-cell activation.
Ding W, Kim SJ, Nair AM, Michael B, Boris-Lawrie K, Tripp A, Feuer G, Lairmore MD
Journal of virology 2003 Oct;77(20):11027-39
Journal of virology 2003 Oct;77(20):11027-39
A glucose-6-phosphate hydrolase, widely expressed outside the liver, can explain age-dependent resolution of hypoglycemia in glycogen storage disease type Ia.
Shieh JJ, Pan CJ, Mansfield BC, Chou JY
The Journal of biological chemistry 2003 Nov 21;278(47):47098-103
The Journal of biological chemistry 2003 Nov 21;278(47):47098-103
N-linked oligosaccharide processing, but not association with calnexin/calreticulin is highly correlated with endoplasmic reticulum-associated degradation of antithrombin Glu313-deleted mutant.
Tokunaga F, Hara K, Koide T
Archives of biochemistry and biophysics 2003 Mar 15;411(2):235-42
Archives of biochemistry and biophysics 2003 Mar 15;411(2):235-42
Tumor-derived, chaperone-rich cell lysate activates dendritic cells and elicits potent antitumor immunity.
Zeng Y, Feng H, Graner MW, Katsanis E
Blood 2003 Jun 1;101(11):4485-91
Blood 2003 Jun 1;101(11):4485-91
Involvement of the endoplasmic reticulum in peroxisome formation.
Geuze HJ, Murk JL, Stroobants AK, Griffith JM, Kleijmeer MJ, Koster AJ, Verkleij AJ, Distel B, Tabak HF
Molecular biology of the cell 2003 Jul;14(7):2900-7
Molecular biology of the cell 2003 Jul;14(7):2900-7
Tyrosinase maturation and oligomerization in the endoplasmic reticulum require a melanocyte-specific factor.
Francis E, Wang N, Parag H, Halaban R, Hebert DN
The Journal of biological chemistry 2003 Jul 11;278(28):25607-17
The Journal of biological chemistry 2003 Jul 11;278(28):25607-17
N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin.
Daniels R, Kurowski B, Johnson AE, Hebert DN
Molecular cell 2003 Jan;11(1):79-90
Molecular cell 2003 Jan;11(1):79-90
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane.
Calvert ME, Digilio LC, Herr JC, Coonrod SA
Reproductive biology and endocrinology : RB&E 2003 Feb 14;1:27
Reproductive biology and endocrinology : RB&E 2003 Feb 14;1:27
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane.
Calvert ME, Digilio LC, Herr JC, Coonrod SA
Reproductive biology and endocrinology : RB&E 2003 Feb 14;1:27
Reproductive biology and endocrinology : RB&E 2003 Feb 14;1:27
Altered levels and regulation of stathmin in paclitaxel-resistant ovarian cancer cells.
Balachandran R, Welsh MJ, Day BW
Oncogene 2003 Dec 4;22(55):8924-30
Oncogene 2003 Dec 4;22(55):8924-30
Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilization.
Payne C, Rawe V, Ramalho-Santos J, Simerly C, Schatten G
Journal of cell science 2003 Dec 1;116(Pt 23):4727-38
Journal of cell science 2003 Dec 1;116(Pt 23):4727-38
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum.
Celli J, de Chastellier C, Franchini DM, Pizarro-Cerda J, Moreno E, Gorvel JP
The Journal of experimental medicine 2003 Aug 18;198(4):545-56
The Journal of experimental medicine 2003 Aug 18;198(4):545-56
Localization of p21-activated protein kinase gamma-PAK/Pak2 in the endoplasmic reticulum is required for induction of cytostasis.
Huang Z, Ling J, Traugh JA
The Journal of biological chemistry 2003 Apr 11;278(15):13101-9
The Journal of biological chemistry 2003 Apr 11;278(15):13101-9
Membrane topology of the hepatitis C virus NS2 protein.
Yamaga AK, Ou JH
The Journal of biological chemistry 2002 Sep 6;277(36):33228-34
The Journal of biological chemistry 2002 Sep 6;277(36):33228-34
Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells.
Ding W, Albrecht B, Kelley RE, Muthusamy N, Kim SJ, Altschuld RA, Lairmore MD
Journal of virology 2002 Oct;76(20):10374-82
Journal of virology 2002 Oct;76(20):10374-82
Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation.
Robin MA, Anandatheerthavarada HK, Biswas G, Sepuri NB, Gordon DM, Pain D, Avadhani NG
The Journal of biological chemistry 2002 Oct 25;277(43):40583-93
The Journal of biological chemistry 2002 Oct 25;277(43):40583-93
N-linked glycosylation is critical for the plasma membrane localization of nephrin.
Yan K, Khoshnoodi J, Ruotsalainen V, Tryggvason K
Journal of the American Society of Nephrology : JASN 2002 May;13(5):1385-9
Journal of the American Society of Nephrology : JASN 2002 May;13(5):1385-9
Cellular location of proteins related to iron absorption and transport.
Simovich MJ, Conrad ME, Umbreit JN, Moore EG, Hainsworth LN, Smith HK
American journal of hematology 2002 Mar;69(3):164-70
American journal of hematology 2002 Mar;69(3):164-70
Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes.
Brosius U, Dehmel T, Gärtner J
The Journal of biological chemistry 2002 Jan 4;277(1):774-84
The Journal of biological chemistry 2002 Jan 4;277(1):774-84
Identification of glycoprotein gpTRL10 as a structural component of human cytomegalovirus.
Spaderna S, Blessing H, Bogner E, Britt W, Mach M
Journal of virology 2002 Feb;76(3):1450-60
Journal of virology 2002 Feb;76(3):1450-60
Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs.
Cabral CM, Liu Y, Moremen KW, Sifers RN
Molecular biology of the cell 2002 Aug;13(8):2639-50
Molecular biology of the cell 2002 Aug;13(8):2639-50
Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum.
Clark RA, Li SL, Pearson DW, Leidal KG, Clark JR, Denning GM, Reddick R, Krause KH, Valente AJ
The Journal of biological chemistry 2002 Aug 30;277(35):32369-78
The Journal of biological chemistry 2002 Aug 30;277(35):32369-78
The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
Bolt G
Archives of virology 2001;146(11):2055-68
Archives of virology 2001;146(11):2055-68
Co-localization of the inositol 1,4,5-trisphosphate receptor and calreticulin in the equatorial segment and in membrane bounded vesicles in the cytoplasmic droplet of human spermatozoa.
Naaby-Hansen S, Wolkowicz MJ, Klotz K, Bush LA, Westbrook VA, Shibahara H, Shetty J, Coonrod SA, Reddi PP, Shannon J, Kinter M, Sherman NE, Fox J, Flickinger CJ, Herr JC
Molecular human reproduction 2001 Oct;7(10):923-33
Molecular human reproduction 2001 Oct;7(10):923-33
nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?
Daniel EE, Jury J, Wang YF
American journal of physiology. Gastrointestinal and liver physiology 2001 Oct;281(4):G1101-14
American journal of physiology. Gastrointestinal and liver physiology 2001 Oct;281(4):G1101-14
nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?
Daniel EE, Jury J, Wang YF
American journal of physiology. Gastrointestinal and liver physiology 2001 Oct;281(4):G1101-14
American journal of physiology. Gastrointestinal and liver physiology 2001 Oct;281(4):G1101-14
Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy.
Hunter RB, Mitchell-Felton H, Essig DA, Kandarian SC
American journal of physiology. Cell physiology 2001 Oct;281(4):C1285-90
American journal of physiology. Cell physiology 2001 Oct;281(4):C1285-90
Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy.
Hunter RB, Mitchell-Felton H, Essig DA, Kandarian SC
American journal of physiology. Cell physiology 2001 Oct;281(4):C1285-90
American journal of physiology. Cell physiology 2001 Oct;281(4):C1285-90
Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: insight into the mechanisms of congenital nephrotic syndrome.
Liu L, Doné SC, Khoshnoodi J, Bertorello A, Wartiovaara J, Berggren PO, Tryggvason K
Human molecular genetics 2001 Nov 1;10(23):2637-44
Human molecular genetics 2001 Nov 1;10(23):2637-44
ER60/ERp57 forms disulfide-bonded intermediates with MHC class I heavy chain.
Lindquist JA, Hämmerling GJ, Trowsdale J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001 Jun;15(8):1448-50
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001 Jun;15(8):1448-50
Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation.
Chen F, Studzinski GP
Blood 2001 Jun 15;97(12):3763-7
Blood 2001 Jun 15;97(12):3763-7
Calreticulin is an interleukin-3-sensitive calcium-binding protein in human basophil leukocytes.
Lyngholm JM, Nielsen HV, Holm M, Schiøtz PO, Johnsen AH
Allergy 2001 Jan;56(1):21-8
Allergy 2001 Jan;56(1):21-8
Endoplasmic reticulum and cis-Golgi localization of human T-lymphotropic virus type 1 p12(I): association with calreticulin and calnexin.
Ding W, Albrecht B, Luo R, Zhang W, Stanley JR, Newbound GC, Lairmore MD
Journal of virology 2001 Aug;75(16):7672-82
Journal of virology 2001 Aug;75(16):7672-82
Carnosic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents.
Danilenko M, Wang X, Studzinski GP
Journal of the National Cancer Institute 2001 Aug 15;93(16):1224-33
Journal of the National Cancer Institute 2001 Aug 15;93(16):1224-33
Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin.
Goicoechea S, Orr AW, Pallero MA, Eggleton P, Murphy-Ullrich JE
The Journal of biological chemistry 2000 Nov 17;275(46):36358-68
The Journal of biological chemistry 2000 Nov 17;275(46):36358-68
Endoplasmic reticulum retention is a common defect associated with tyrosinase-negative albinism.
Halaban R, Svedine S, Cheng E, Smicun Y, Aron R, Hebert DN
Proceedings of the National Academy of Sciences of the United States of America 2000 May 23;97(11):5889-94
Proceedings of the National Academy of Sciences of the United States of America 2000 May 23;97(11):5889-94
Rat sperm 2B1 glycoprotein (PH20) contains a C-terminal sequence motif for attachment of a glycosyl phosphatidylinositol anchor. Effects of endoproteolytic cleavage on hyaluronidase activity.
Seaton GJ, Hall L, Jones R
Biology of reproduction 2000 Jun;62(6):1667-76
Biology of reproduction 2000 Jun;62(6):1667-76
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
VanSlyke JK, Deschenes SM, Musil LS
Molecular biology of the cell 2000 Jun;11(6):1933-46
Molecular biology of the cell 2000 Jun;11(6):1933-46
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
VanSlyke JK, Deschenes SM, Musil LS
Molecular biology of the cell 2000 Jun;11(6):1933-46
Molecular biology of the cell 2000 Jun;11(6):1933-46
Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity.
Chillarón J, Haas IG
Molecular biology of the cell 2000 Jan;11(1):217-26
Molecular biology of the cell 2000 Jan;11(1):217-26
HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern.
Wainwright SD, Biro PA, Holmes CH
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):319-28
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):319-28
Caveolae from canine airway smooth muscle contain the necessary components for a role in Ca(2+) handling.
Darby PJ, Kwan CY, Daniel EE
American journal of physiology. Lung cellular and molecular physiology 2000 Dec;279(6):L1226-35
American journal of physiology. Lung cellular and molecular physiology 2000 Dec;279(6):L1226-35
Caveolae from canine airway smooth muscle contain the necessary components for a role in Ca(2+) handling.
Darby PJ, Kwan CY, Daniel EE
American journal of physiology. Lung cellular and molecular physiology 2000 Dec;279(6):L1226-35
American journal of physiology. Lung cellular and molecular physiology 2000 Dec;279(6):L1226-35
Different expression of calreticulin and immunoglobulin binding protein in Alzheimer's disease brain.
Taguchi J, Fujii A, Fujino Y, Tsujioka Y, Takahashi M, Tsuboi Y, Wada I, Yamada T
Acta neuropathologica 2000 Aug;100(2):153-60
Acta neuropathologica 2000 Aug;100(2):153-60
Specific association of increased cyclin-dependent kinase 5 expression with monocytic lineage of differentiation of human leukemia HL60 cells.
Chen F, Rao J, Studzinski GP
Journal of leukocyte biology 2000 Apr;67(4):559-66
Journal of leukocyte biology 2000 Apr;67(4):559-66
Evidence of [Ca(2+)]i elevation by anti-calreticulin immunoreactive protein in neurons.
Hossain MA, Murayama N, Oka T, Nakajima T
Neuroscience research 2000 Apr;36(4):285-90
Neuroscience research 2000 Apr;36(4):285-90
Calreticulin couples calcium release and calcium influx in integrin-mediated calcium signaling.
Kwon MS, Park CS, Choi K, Ahnn J, Kim JI, Eom SH, Kaufman SJ, Song WK
Molecular biology of the cell 2000 Apr;11(4):1433-43
Molecular biology of the cell 2000 Apr;11(4):1433-43
Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at ser128.
Anandatheerthavarada HK, Biswas G, Mullick J, Sepuri NB, Otvos L, Pain D, Avadhani NG
The EMBO journal 1999 Oct 15;18(20):5494-504
The EMBO journal 1999 Oct 15;18(20):5494-504
Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity.
Basu S, Srivastava PK
The Journal of experimental medicine 1999 Mar 1;189(5):797-802
The Journal of experimental medicine 1999 Mar 1;189(5):797-802
Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity.
Basu S, Srivastava PK
The Journal of experimental medicine 1999 Mar 1;189(5):797-802
The Journal of experimental medicine 1999 Mar 1;189(5):797-802
Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules.
Arosa FA, de Jesus O, Porto G, Carmo AM, de Sousa M
The Journal of biological chemistry 1999 Jun 11;274(24):16917-22
The Journal of biological chemistry 1999 Jun 11;274(24):16917-22
ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.
Oliver JD, Roderick HL, Llewellyn DH, High S
Molecular biology of the cell 1999 Aug;10(8):2573-82
Molecular biology of the cell 1999 Aug;10(8):2573-82
Spreading of the immune response from 52 kDaRo and 60 kDaRo to calreticulin in experimental autoimmunity.
Kinoshita G, Keech CL, Sontheimer RD, Purcell A, McCluskey J, Gordon TP
Lupus 1998;7(1):7-11
Lupus 1998;7(1):7-11
Calnexin association is not sufficient to protect T cell receptor alpha proteins from rapid degradation in CD4+CD8+ thymocytes.
Bennett MJ, Van Leeuwen JE, Kearse KP
The Journal of biological chemistry 1998 Sep 11;273(37):23674-80
The Journal of biological chemistry 1998 Sep 11;273(37):23674-80
Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins.
Choukhi A, Ung S, Wychowski C, Dubuisson J
Journal of virology 1998 May;72(5):3851-8
Journal of virology 1998 May;72(5):3851-8
Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins.
Choukhi A, Ung S, Wychowski C, Dubuisson J
Journal of virology 1998 May;72(5):3851-8
Journal of virology 1998 May;72(5):3851-8
Calnexin associates with monomeric and oligomeric (disulfide-linked) CD3delta proteins in murine T lymphocytes.
Kearse KP
The Journal of biological chemistry 1998 Jun 5;273(23):14152-7
The Journal of biological chemistry 1998 Jun 5;273(23):14152-7
Calnexin associates with monomeric and oligomeric (disulfide-linked) CD3delta proteins in murine T lymphocytes.
Kearse KP
The Journal of biological chemistry 1998 Jun 5;273(23):14152-7
The Journal of biological chemistry 1998 Jun 5;273(23):14152-7
Vasostatin, a calreticulin fragment, inhibits angiogenesis and suppresses tumor growth.
Pike SE, Yao L, Jones KD, Cherney B, Appella E, Sakaguchi K, Nakhasi H, Teruya-Feldstein J, Wirth P, Gupta G, Tosato G
The Journal of experimental medicine 1998 Dec 21;188(12):2349-56
The Journal of experimental medicine 1998 Dec 21;188(12):2349-56
MHC class I molecules compete in the endoplasmic reticulum for access to transporter associated with antigen processing.
Knittler MR, Gülow K, Seelig A, Howard JC
Journal of immunology (Baltimore, Md. : 1950) 1998 Dec 1;161(11):5967-77
Journal of immunology (Baltimore, Md. : 1950) 1998 Dec 1;161(11):5967-77
Differential modulation of SERCA2 isoforms by calreticulin.
John LM, Lechleiter JD, Camacho P
The Journal of cell biology 1998 Aug 24;142(4):963-73
The Journal of cell biology 1998 Aug 24;142(4):963-73
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
Lindquist JA, Jensen ON, Mann M, Hämmerling GJ
The EMBO journal 1998 Apr 15;17(8):2186-95
The EMBO journal 1998 Apr 15;17(8):2186-95
Calreticulin associates with stress proteins: implications for chaperone function during heat stress.
Jethmalani SM, Henle KJ
Journal of cellular biochemistry 1998 Apr 1;69(1):30-43
Journal of cellular biochemistry 1998 Apr 1;69(1):30-43
High density distribution of endoplasmic reticulum proteins and mitochondria at specialized Ca2+ release sites in oligodendrocyte processes.
Simpson PB, Mehotra S, Lange GD, Russell JT
The Journal of biological chemistry 1997 Sep 5;272(36):22654-61
The Journal of biological chemistry 1997 Sep 5;272(36):22654-61
Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells.
Halaban R, Cheng E, Zhang Y, Moellmann G, Hanlon D, Michalak M, Setaluri V, Hebert DN
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6210-5
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6210-5
Calreticulin biosynthesis and processing in human myeloid cells: demonstration of signal peptide cleavage and N-glycosylation.
Denning GM, Leidal KG, Holst VA, Iyer SS, Pearson DW, Clark JR, Nauseef WM, Clark RA
Blood 1997 Jul 1;90(1):372-81
Blood 1997 Jul 1;90(1):372-81
Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand.
Barsony J, Renyi I, McKoy W
The Journal of biological chemistry 1997 Feb 28;272(9):5774-82
The Journal of biological chemistry 1997 Feb 28;272(9):5774-82
Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand.
Barsony J, Renyi I, McKoy W
The Journal of biological chemistry 1997 Feb 28;272(9):5774-82
The Journal of biological chemistry 1997 Feb 28;272(9):5774-82
Interactions between newly synthesized glycoproteins, calnexin and a network of resident chaperones in the endoplasmic reticulum.
Tatu U, Helenius A
The Journal of cell biology 1997 Feb 10;136(3):555-65
The Journal of cell biology 1997 Feb 10;136(3):555-65
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.
Ortmann B, Copeman J, Lehner PJ, Sadasivan B, Herberg JA, Grandea AG, Riddell SR, Tampé R, Spies T, Trowsdale J, Cresswell P
Science (New York, N.Y.) 1997 Aug 29;277(5330):1306-9
Science (New York, N.Y.) 1997 Aug 29;277(5330):1306-9
The related molecular chaperones calnexin and calreticulin differentially associate with nascent T cell antigen receptor proteins within the endoplasmic reticulum.
Van Leeuwen JE, Kearse KP
The Journal of biological chemistry 1996 Oct 11;271(41):25345-9
The Journal of biological chemistry 1996 Oct 11;271(41):25345-9
Deglucosylation of N-linked glycans is an important step in the dissociation of calreticulin-class I-TAP complexes.
van Leeuwen JE, Kearse KP
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):13997-4001
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):13997-4001
Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes.
Hebert DN, Foellmer B, Helenius A
The EMBO journal 1996 Jun 17;15(12):2961-8
The EMBO journal 1996 Jun 17;15(12):2961-8
Calreticulin expression in spinal motoneurons of the rat.
Copray JC, Liem RS, Kernell D
Journal of chemical neuroanatomy 1996 Jul;11(1):57-65
Journal of chemical neuroanatomy 1996 Jul;11(1):57-65
Intracellular calcium stores and inositol 1,4,5-trisphosphate receptor in rat liver cells.
Lièvremont JP, Hill AM, Tran D, Coquil JF, Stelly N, Mauger JP
The Biochemical journal 1996 Feb 15;314 ( Pt 1)(Pt 1):189-97
The Biochemical journal 1996 Feb 15;314 ( Pt 1)(Pt 1):189-97
Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.
Peterson JR, Ora A, Van PN, Helenius A
Molecular biology of the cell 1995 Sep;6(9):1173-84
Molecular biology of the cell 1995 Sep;6(9):1173-84
Calreticulin inhibits repetitive intracellular Ca2+ waves.
Camacho P, Lechleiter JD
Cell 1995 Sep 8;82(5):765-71
Cell 1995 Sep 8;82(5):765-71
Calreticulin inhibits repetitive intracellular Ca2+ waves.
Camacho P, Lechleiter JD
Cell 1995 Sep 8;82(5):765-71
Cell 1995 Sep 8;82(5):765-71
Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading.
White TK, Zhu Q, Tanzer ML
The Journal of biological chemistry 1995 Jul 7;270(27):15926-9
The Journal of biological chemistry 1995 Jul 7;270(27):15926-9
Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading.
White TK, Zhu Q, Tanzer ML
The Journal of biological chemistry 1995 Jul 7;270(27):15926-9
The Journal of biological chemistry 1995 Jul 7;270(27):15926-9
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils.
Stendahl O, Krause KH, Krischer J, Jerström P, Theler JM, Clark RA, Carpentier JL, Lew DP
Science (New York, N.Y.) 1994 Sep 2;265(5177):1439-41
Science (New York, N.Y.) 1994 Sep 2;265(5177):1439-41
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils.
Stendahl O, Krause KH, Krischer J, Jerström P, Theler JM, Clark RA, Carpentier JL, Lew DP
Science (New York, N.Y.) 1994 Sep 2;265(5177):1439-41
Science (New York, N.Y.) 1994 Sep 2;265(5177):1439-41
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot was performed using Calreticulin Polyclonal Antibody (Product # PA3-900) and a ~55kDa band corresponding to Calreticulin was observed across all the cell lines tested with a uncharacterized bands (*). Whole cell extracts (30 µg lysate) of HL-60 (Lane 1), LNCaP (Lane 2), HeLa (Lane 3), MCF-7 (Lane 4), Mouse Liver (Lane 5) and Rat Liver (Lane 6) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was probed with the primary antibody (1:1000 dilution) and detected by chemiluminescence with Goat anti-Rabbit IgG (H+L) Superclonal™ Recombinant Secondary Antibody, HRP (Product # A27036, 1:4000 dilution) using the iBright FL 1000 (Product # A32752). Chemiluminescent detection was performed using Novex® ECL Chemiluminescent Substrate Reagent Kit (Product # WP20005).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Knockout of Calreticulin was achieved by CRISPR-Cas9 genome editing using LentiArray™ Lentiviral sgRNA (Product # A32042, Assay ID CRISPR1007602_LV) and LentiArray Cas9 Lentivirus (Product # A32064). Western blot analysis of Calreticulin was performed by loading 30 µg of HeLa wild type (Lane 1), HeLa Cas9 (Lane 2) and HeLa Calreticulin KO (Lane 3) whole cell extracts. The samples were electrophoresed using NuPAGE™ Novex™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was probed with Calreticulin Polyclonal Antibody (Product # PA3-900, 1:1000 dilution) and Goat anti-Rabbit IgG (H+L) Superclonal™ Recombinant Secondary Antibody, HRP (Product # A27036, 1:10,000 dilution) using the iBright™ FL1500 (Product # A44115). Chemiluminescent detection was performed usingSuperSignal™ West Dura Extended Duration Substrate (Product # 34076). Loss of signal upon CRISPR mediated knockout (KO) using the LentiArray™ CRISPR product line confirms that antibody is specific to Calreticulin. Uncharacterized band was observed in Lane 1 and 2 at ~50 kDa.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
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- Experimental details
- Immunofluorescent analysis of Calreticulin (green) U2OS cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in PBS for 10 minutes at room temperature and blocked with 2% BSA in PBS 0.1% triton-X (Product # 37525) for 30 minutes at room temperature. Cells were probed with a rabbit polyclonal antibody recognizing Calreticulin (Product # PA3-900) at a dilution of 1:50 for at least 1 hour at room temperature. Cells were washed with PBS and incubated with DyLight 488 goat-anti-rabbit IgG secondary antibody (Product # 35552) at a dilution of 1:250 for 30 minutes at room temperature. Actin filaments (red) were stained with DyLight 554-Phalloidin (Product # 21834) at a dilution of 1:300 (i.e. 1unit/mL final concentration) in PBS and incubated for 30 min including. Nuclei (blue) were stained with Hoechst 33342 dye (Product # 62249) at a dilution of 1 µg/mL. Images were taken on a Thermo Scientific ArrayScan VTI at 20X magnification.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Calreticulin using anti-Calreticulin polyclonal antibody (Product # PA3-900) shows staining in A549 Cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Calreticulin using anti-Calreticulin polyclonal antibody (Product # PA3-900) shows staining in HMVEC Cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Calreticulin using anti-Calreticulin polyclonal antibody (Product # PA3-900) shows staining in NS-1 Cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Calreticulin using anti-Calreticulin polyclonal antibody (Product # PA3-900) shows staining in p19 Cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Phalloidin (purple) and Calreticulin (green) in A431 cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in PBS for 10 minutes at room temperature and blocked with 2% BSA (Product # 37525) in PBS + 0.1% Triton X-100 for 30 minutes at room temperature. Cells were probed with a Calreticulin polyclonal antibody (Product # PA3-900) at a dilution of 1:75 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-rabbit IgG secondary antibody (Product # 35552) at a dilution of 1:250 for 30 minutes at room temperature. Actin was stained with DyLight 650 Phalloidin (Product # 21838) at a dilution of 1:120 (2.5 units/mL final concentration) and nuclei (blue) were stained with Hoechst (Product # 62249) at a concentration of 1 µg/mL for 30 minutes. Images were taken on a Zeiss Axio Observer Z1 microscope at 20X magnification.
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Phalloidin (blue) and Calreticulin (green) in A431 cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in PBS for 10 minutes at room temperature and blocked with 2% BSA in PBS + 0.1% Triton X-100 (Product # 37525) for 30 minutes at room temperature. Cells were probed with a Calreticulin polyclonal antibody (Product # PA3-900) at a dilution of 1:75 for at least 1 hour at room temperature, washed with PBS, and incubated with Dylight 488 goat anti-rabbit IgG secondary antibody (Product # 35552) at a dilution of 1:250 for 30 minutes at room temperature. Actin was stained with Dylight 350 Phalloidin (Product # 21830) at a dilution of 1:120 (2.5units/mL final concentration) and nuclei (red) were stained with DRAQ5 (Product # 62254) at a concentration of 1 µg/mL for 30 minutes. Images were taken on a Zeiss Axio Observer Z1 microscope at 20X magnification.
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Phalloidin (green) and Calreticulin (red) in U2OS cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in PBS for 10 minutes at room temperature and blocked with 2% BSA (Product # 37525) in PBS + 0.1% Triton X-100 for 30 minutes at room temperature. Cells were probed with a Calreticulin polyclonal antibody (Product # PA3-900) at a dilution of 1:75 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 633 goat anti-rabbit IgG secondary antibody (Product # 35562) at a dilution of 1:250 for 30 minutes at room temperature. Actin was stained with DyLight 488 Phalloidin (Product # 21833) at a dilution of 1:300 (1 unit/mL final concentration) and nuclei (blue) were stained with Hoechst (Product # 62249) at a concentration of 1 µg/mL for 30 minutes. Images were taken on a Thermo Scientific ArrayScan VTI at 20X magnification.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Phalloidin (orange) and Calreticulin (green) in A431 cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in PBS for 10 minutes at room temperature and blocked with 2% BSA (Product # 37525) in PBS + 0.1% Triton X-100 for 30 minutes at room temperature. Cells were probed with a Calreticulin polyclonal antibody (Product # PA3-900) at a dilution of 1:75 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-rabbit IgG secondary antibody (Product # 35552) at a dilution of 1:250 for 30 minutes at room temperature. Actin was stained with DyLight 550 Phalloidin (Product # 21835) at a dilution of 1:120 (2.5 units/mL final concentration) and nuclei (blue) were stained with Hoechst (Product # 62249) at a concentration of 1 µg/mL for 30 minutes. Images were taken on a Zeiss Axio Observer Z1 microscope at 20X magnification.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunolocalization of calreticulin in rat brain cortex using Product # PA3-900.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
