Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ADI-SPA-601PE-F - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-SPA-601PE-F, RRID:AB_11180758
- Product name
- Calreticulin monoclonal antibody (FMC 75) (PE conjugate)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein G affinity purified.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- FMC 75
- Vial size
- 200 μg
- Storage
- +4°C
- Handling
- Avoid freeze/thaw cycles. Protect from light.
Submitted references CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans.
Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
Immunogenic tumor cell death induced by chemoradiotherapy in patients with esophageal squamous cell carcinoma.
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.
Martinez-Torres AC, Quiney C, Attout T, Boullet H, Herbi L, Vela L, Barbier S, Chateau D, Chapiro E, Nguyen-Khac F, Davi F, Le Garff-Tavernier M, Moumné R, Sarfati M, Karoyan P, Merle-Béral H, Launay P, Susin SA
PLoS medicine 2015 Mar;12(3):e1001796
PLoS medicine 2015 Mar;12(3):e1001796
Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
Blood 2012 Nov 8;120(19):4058-67
Blood 2012 Nov 8;120(19):4058-67
Immunogenic tumor cell death induced by chemoradiotherapy in patients with esophageal squamous cell carcinoma.
Suzuki Y, Mimura K, Yoshimoto Y, Watanabe M, Ohkubo Y, Izawa S, Murata K, Fujii H, Nakano T, Kono K
Cancer research 2012 Aug 15;72(16):3967-76
Cancer research 2012 Aug 15;72(16):3967-76
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.
Chao MP, Jaiswal S, Weissman-Tsukamoto R, Alizadeh AA, Gentles AJ, Volkmer J, Weiskopf K, Willingham SB, Raveh T, Park CY, Majeti R, Weissman IL
Science translational medicine 2010 Dec 22;2(63):63ra94
Science translational medicine 2010 Dec 22;2(63):63ra94
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Flow Cytometry