NDUFB5

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Description

NADH:ubiquinone oxidoreductase subunit B5

Tissue specificity

Tissue enhanced (skeletal muscle)

Subcell location

Nucleoplasm, Mitochondria

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (179604690 - 179627647)

Ensembl ID

ENSG00000136521  (ver. 103.38)

Orthologs

-

UniProt

O43674

neXtProt

NX_O43674

Human splice variants

Protein structure